NC3Rs Workshop: ‘Toxicokinetics and the 3Rs'

Event:   NC3Rs NC3Rs
Event date:
29 May 2008
Event location:Central London

Event description:


The NC3Rs held a 1-day workshop on 29 May 2008 to discuss the role of toxicokinetic information in improving the risk assessment of chemicals and advancing the 3Rs in regulatory toxicology testing. The following questions were considered at the workshop:

  •  What is the potential use and value of integrated
     toxicokinetic information for hazard identification and risk assessment of chemicals?
  • Can the further use of toxicokinetic information
    in hazard identification and risk assessment lead to advances in the 3Rs and if so how?

Particular emphasis was placed on how toxicokinetic information is, or could be, applied in the different chemical industry sectors. In particular, on the potential value and transferability of approaches currently applied in the pharmaceutical sector, and beginning to be applied in the agrochemical sector.

The following themes were addressed by the speakers and in the discussion groups:

  • The role of toxicokinetics in hazard identification: scope for the 3Rs
  • The role of toxicokinetics in risk assessment: scope for the 3Rs
  • 3Rs methods for generation of toxicokinetic information

Participants from all sectors of the chemical and pharmaceutical industries, regulatory authorities and agencies, and scientific researchers in the fields of toxicokinetics and regulatory toxicology were invited to attend the workshop. For further information see the programme (PDF, 89KB).

Related Documents

link arrow 'Toxicokinetics and the 3Rs' Programme (PDF, 58KB)