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Invited Articles

Mathematical models in cardiac electrophysiology research – implications for the 3Rs

Martin Fink, Penelope J Noble & Denis Noble FRS, Department of Physiology, Anatomy, and Genetics, University of Oxford 

An improved containment system for experimentally infected macaques

Dr Mike J Dennis, Health Protection Agency, Centre for Emergency Preparedness and Response 

Nanotechnology: applying the 3Rs to risk assessment

Dr Barry Park, Oxonica & Dr Patricia Martin, Product Assessment and Regulatory Compliance  

Automated blood sampling and the 3Rs

Ann Holmberg, DiLab AB, and Robert Pelletier, DiLab Inc.  

Botulinum toxin: applying the 3Rs to product potency testing

Dr Dorothea Sesardic and Dr Rose Gaines Das, National Institute for Biological Standards and Control 

Intelligent testing strategies in ecotoxicology

Professor Tom Hutchinson, Plymouth Marine Laboratory 

The LifeShirt PreClinical System is a significant advance towards answering the call of the 3Rs

Dr P. Alexander Derchak, VivoMetrics Inc. 

Validating refinements to laboratory housing: asking the animals

Dr Chris M Sherwin, Centre for Behavioural Biology, Department of Clinical Veterinary Science, University of Bristol 

Identifying laboratory rodents using earprints

Mr Jens Cameron, DiLab, Sweden; Dr Christina Jacobson, AstraZeneca R&D, Sweden; Dr Kenneth Nilsson, Halmstad University, Sweden; Professor Thorsteinn Rögnvaldsson, Halmstad University, Sweden 

Zebrafish as an alternative model organism for disease modelling and drug discovery: implications for the 3Rs

Dr Angeleen Fleming, Cambridge Institute for Medical Research