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Spontaneously beating human cardiac microtissue scoops 3Rs poster prize
Prize awarded for in vitro method that could replace dog cardiomyocytes in cardiotoxicity assays
24 June 2013
Research to develop a human cardiac microtissue model that beats spontaneously has won first place in last week's joint NC3Rs and Society of Biology symposium on 3Rs advances.
Miss Stephanie Ravenscroft, MRC Centre for Drug Safety
Science at the University of Liverpool, and AstraZeneca, was
awarded £1000 for the research, which may provide a human
relevant model to replace the use of dog cardiomyocytes in
functional contractility assays to investigate cardiotoxicity.
Cardiotoxicity is a major cause of drug withdrawal from the
market and of attrition during drug development.
The poster was one of 28 presented by researchers at this year's symposium, which was attended by over 150 delegates and themed around maximising information from mouse models and new techniques to reduce or replace the use of animals in research.
Two runners-up were each awarded prizes of £500:
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