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NC3Rs announced as a consortium partner in new Horizon 2020 project: EU-ToxRisk

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The NC3Rs has been announced as a consortium partner for a new collaborative project awarded under the Horizon 2020 framework, in which academia will work alongside small and medium-sized enterprises (SMEs), large industry, contract research organisations (CROs) and regulatory bodies to achieve more efficient and animal-free chemical safety assessments in toxicology.

The European Commission has pledged €30 Million for a consortium of 39 partner organisations to work on the integration of new concepts for regulatory chemical safety assessment. The work, which is co-ordinated by Leiden University, will involve cutting-edge human-relevant in vitro non-animal methods and in silico computational technologies to translate molecular mechanistic understanding of toxicity into safety testing strategies. The ultimate goal is to deliver reliable, animal-free hazard and risk assessment of chemicals.

We lead an extensive programme of work in toxicology and regulatory science, working closely with experts from academia, industry scientists as well as regulators to support changes in policy and practice which accelerate the application of the 3Rs in chemical and pharmaceutical safety assessment. Our role within the EU-ToxRisk project will involve working alongside regulators to define and review the regulatory framework of the project; to aid in the co-ordination and provision of training to regulators; to advise on how best to integrate the 3Rs into risk assessment based on the project outcomes; and support the development of OECD guidance relevant to this project.

Download the full press release regarding EU-ToxRisk.