Latest news and blogs
Tuesday 15 March 2016
A study describes a new method to grow a drug resistant sub-population of cancer stem cells (CSCs) in vitro, providing an opportunity to screen compounds that target these cells using fewer animals.
Wednesday 09 March 2016
Three projects have each been awarded £30,000 seed funding, through the NC3Rs CRACK IT Solutions partnering programme, to support collaborations which will help develop, validate and test technologies with 3Rs potential. The programme links technology developers with researchers and organisations that can add...
New CRACK IT Solution: Extrapolating in vitro to in vivo toxicity for predicting effects on growth in rats and mice
Tuesday 08 March 2016
Researchers at the University of York are seeking partners with expertise in mammalian cell culture to develop novel mathematical approaches for in vitro to in vivo extrapolation. Such models developed as part of a suite of tests have the potential to reduce the use of animals in chronic toxicity studies. The...
Monday 29 February 2016
Three pieces of outstanding published research with 3Rs impacts have been given awards in this year’s 3Rs Prize competition, run by the NC3Rs, and sponsored by GlaxoSmithKline (GSK). The Prize ceremony is taking place today (29 February) with 150 guests from across the scientific community attending. The 3Rs...
Latest CRACK IT Challenges: funding innovative technologies with 3Rs benefits and business potential
Monday 29 February 2016
Six teams have been awarded funding in Phase 1 of the latest NC3Rs CRACK IT Challenges competition, a challenge-led competition run in collaboration with the UK’s innovation agency, Innovate UK, using its Small Business Research Initiative (SBRI). CRACK IT Challenges bring together industry, academia and SMEs...
Thursday 18 February 2016
A new e-learning training package designed to help researchers and animal care staff identify signs of good and poor welfare in laboratory animals has been launched online. The free resource, developed by Professor Paul Flecknell and his team at Newcastle University, is the second e-learning module to be...
Tuesday 16 February 2016
Fish are commonly used in experiments to identify environmental hazards and pollutants in water. As their gills are in constant contact with the water, they are often the focal point for studies seeking to understand the effects of exposure to toxicants.
Thursday 11 February 2016
Bovine tuberculosis (bTB) is one of the biggest challenges facing the cattle farming industry in the UK. Here we describe how current animal models of bovine tuberculosis have been identified as a major bottleneck to progress by scientists working in the field, and how the NC3Rs is working with other funders to...
Thursday 04 February 2016
The ARRIVE guidelines were launched in 2010, and since their publication the scientific community have been using the guidelines to improve the reporting of animal research. Figures published today in Nature reflect the growing support from journals; see Nature Trend Watch ‘Surge in support for animal-research...
Promising research on neuronal ageing in a non-mammalian model recognised by David Sainsbury Fellowship
Wednesday 03 February 2016
Invertebrates such as Drosophila melanogaster (the fruit fly) are used extensively in research on complex biological processes and disease mechanisms. They have the potential to replace the use of mammalian models in some studies, particularly in rodents, but maximising this opportunity is challenging and...
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