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ARRIVE guidelines

**Animal Research: Reporting of In Vivo Experiments**

ARRIVE guidelines (PDF, 55KB)

These guidelines are intended to improve the reporting of animal experiments and have been published in the journal PLoS Biology and five other journals. Previous work by the NC3Rs has shown that many publications reporting publicly funded animal research from the UK and US lack key information on how the study was designed, conducted and analysed, which could limit their value in informing future scientific studies and policy.

The ARRIVE (Animal Research: Reporting In Vivo Experiments) guidelines have been developed by the NC3Rs to improve standards of reporting and ensure that the data from animal experiments can be fully evaluated and utilised. The guidelines are primarily aimed at scientists writing up their research for publication or involved in peer review.

Developed in consultation with the scientific community, including researchers, statisticians, journal editors, and funders, the guidelines consist of a 20-point checklist of the essential information that should be included in publications reporting animal research.

The UK's major bioscience funders, including the MRC, BBSRC, Defra, NERC and the Wellcome Trust, have incorporated adherence to the guidelines into a revised version of 'Responsibility in the use of animals in bioscience research: Expectations of the major research council and charitable funding bodies', which was originally published in May 2008.

Press release: Guidelines ARRIVE to improve reporting of animal research

PLoS Biology perspective: Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research

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