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The following 13 research projects were funded by the NC3Rs in 2010.
Professor David Baker and Dr Mark Baker, Queen Mary, University of London (£368,512)
2Rs (refining and reducing) of animal models of multiple sclerosis
Professor Wendy Barclay, Imperial College London (£125,368)
Highly differentiated cultures of ferret airway epithelium for the study of respiratory viruses, including influenza
Dr Caroline Brennan, Queen Mary, University of London (£356,952)
Zebrafish behavioural assays to identify genetic mechanisms underlying drug seeking and addiction
Dr Louis Chesler, Dr Suzanne Eccles and Professor Andrew Pearson, Institute of Cancer Research (£291,488)
Replacement of animals in cancer drug development by using 3D in vitro functional assays for increased predictive power
Professor Sian Harding and Dr Nadire Ali, Imperial College London (£323,316)
Stem cell-derived cardiomyocytes for detection of cardiotoxicity in cancer therapeutics
Professor Christer Hogstrand and Dr Nic Bury, King's College London and Dr Peter Kille, Cardiff University (£386,300)
FIGCS: An in vitro model to replace ecotoxicity testing of fish to pharmaceuticals
Dr Peter Hohenstein and Professor Nicholas Hastie, MRC Human Genetics Unit, and Professor Jamie Davies, University of Edinburgh (£428,344)
Reducing mouse number in complex genetic experiments
Professor Charles Vyvyan Howard, Dr George McKerr, Dr Kurt Saetzler and Professor Ana Soto, University of Ulster (£361,934)
A 3-D tissue model of breast morphogenesis for replacing animals in testing for endocrine disrupting substances
Dr Roland Jones, University of Bath (£362,968)
A chronic model of epilepsy in organotypic brain slice cultures of the rat entorhinal cortex
Dr Mohammed Nassar, Professor David Grundy and Professor Mathew Holley, University of Sheffield (£387,392)
Derivation of conditionally immortalised mouse DRG cell lines
Dr Owen Sansom and Dr Marcos Vidal, University of Glasgow (£350,528)
Using the Drosophila fly intestine to investigate Wnt targets in vivo
Professor Christopher Secombes, Dr Yolanda Corripio-Miyar and Dr Jun Zou, University of Aberdeen (£156,812)
Development of in vitro assays to determine vaccine efficacy in fish
Dr Dorothea Sesardic, Dr Christine Escargueil and Dr Roland Fleck, National Institute for Biological Standards and Control (NIBSC) (£337,308)
Development of cell based assays as replacement assays for botulinum toxins and antitoxins
Thirteen research projects were funded in 2009.
Ten research projects were funded in 2008.
Eleven research projects were funded in 2007.
Nine research projects were funded in 2006.
Eight research projects were funded in 2005.
Three research projects were funded in 2004.
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