NC3Rs RSS Feed

New cancer 3D technology helps to reduce animal experiments

Tue, 27 Jul 2010 00:00:00 GMT

Over £4 million for 13 research projects that aim to replace, reduce or refine the use of animals in research and testing was announced on 26 July 2010 by the NC3Rs.

New policy on custom-made antibodies

Tue, 13 Jul 2010 00:00:00 GMT

Animal welfare standards expected of suppliers

Pseudoislets as primary islet replacements for research: report on a symposium at King's College London, London UK

Thu, 1 Jul 2010 00:00:00 GMT

Laboratory-based research aimed at understanding processes regulating insulin secretion and mechanisms underlying ß-cell dysfunction and loss in diabetes often makes use of rodents, as these processes are in many respects similar between rats/mice and humans. Inde

Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research

Tue, 29 Jun 2010 00:00:00 GMT

In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of open-access journals has revolutionised the publication process, maximising the availability of

Guidelines ARRIVE to improve reporting of animal experiments

Tue, 29 Jun 2010 00:00:00 GMT

NC3Rs seeking new Board Members

Mon, 21 Jun 2010 00:00:00 GMT

Deadline for applications is 31 July 2010

EPAA 3Rs Communication Prize

Wed, 16 Jun 2010 00:00:00 GMT

Deadline for submissions is 15 September 2010

Welfare of the minipig with special reference to use in regulatory toxicology

Mon, 31 May 2010 00:00:00 GMT

This paper reviews the animal welfare challenges associated with the use of minipigs in toxicology testing, and compares these to published knowledge on the other widely used non-rodent species (dogs and non-human primates). Welfare challenges arise from housing and man

Revised guidelines for the welfare of animals in cancer research

Thu, 27 May 2010 00:00:00 GMT

Guidelines for the welfare and use of animals in cancer research have been published in the British Journal of Cancer

Guidelines for the welfare and use of animals in cancer research

Tue, 25 May 2010 00:00:00 GMT

Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer. Excellent standards of animal care are fully consistent with the conduct of high quality cancer r

Cross-sector review of drivers and available 3Rs approaches for acute systemic toxicity testing

Wed, 19 May 2010 00:00:00 GMT

Acute systemic toxicity studies are carried out in many sectors in which synthetic chemicals are manufactured or used, and are among the most criticized of all toxicology tests on both scientific and ethical grounds. A review of the drivers for acute toxicity testing wi

Newcastle University to investigate euthanasia of laboratory rodents

Mon, 17 May 2010 00:00:00 GMT

The NC3Rs has selected Newcastle University to receive a strategic award of £300k to establish methods of humane killing of laboratory rodents

Review highlights opportunities to avoid unnecessary acute toxicity testing

Wed, 10 Mar 2010 00:00:00 GMT

Leaflet of key points produced to disseminate findings more widely

Recent advances in telemetry promote further progress in reduction and refinement

Wed, 10 Mar 2010 00:00:00 GMT

Jessica E. Grenwis, Data Sciences International (DSI)

Responsible research

Mon, 1 Mar 2010 00:00:00 GMT

The rate of new drug approvals has remained largely unchanged for 60 years, despite a huge increase in investment (currently at $50 billion per year). It has been documented on a regular basis that the drug development model has become unaffordable, is limited in its cu

Opportunities to minimise animal testing under REACH

Thu, 25 Feb 2010 00:00:00 GMT

New leaflet published by the UK Health and Safety Executive (HSE)

Funding available from CAAT to find alternatives in toxicology

Wed, 10 Feb 2010 00:00:00 GMT

Apply for funding to help implement 'Toxicity Testing in the 21st Century'

New way to grow embryonic stem cells holds promise of dramatic reduction in animal use

Wed, 27 Jan 2010 00:00:00 GMT

The winner of this year's annual NC3Rs 3Rs Prize has developed a new method of priming early embryos to form embryonic stem (ES) cells

The future of non-human primate use in mAb development

Thu, 21 Jan 2010 00:00:00 GMT

It has been predicted that the use of non-human primates (NHPs) is going to increase considerably in the development of monoclonal antibodies (mAbs). Opportunities exist to focus on a rigorous, science-based approach to drug development, however, which will minimize thi

Acute toxicity testing of chemicals: opportunities to avoid redundant testing and use alternative approaches

Fri, 1 Jan 2010 00:00:00 GMT

Assessment of the acute systemic oral, dermal, and inhalation toxicities, skin and eye irritancy, and skin sensitisation potential of chemicals is required under regulatory schemes worldwide. In vivo studies conducted to assess these endpoints can sometimes be

Studentships awarded to attract top graduates to the 3Rs

Wed, 2 Dec 2009 00:00:00 GMT

The NC3Rs has awarded its first PhD studentships to five leading UK research groups

Survey of the quality of experimental design, statistical analysis and reporting of research using laboratory animals

Mon, 30 Nov 2009 00:00:00 GMT

For scientific, ethical and economic reasons, experiments involving animals should be appropriately designed, correctly analysed and transparently reported. This increases the scientific validity of the results, and maximises the knowledge gained from each experiment. A

Mathematical models in cardiac electrophysiology research: implications for the 3Rs

Mon, 30 Nov 2009 00:00:00 GMT

Martin Fink, Penelope J Noble & Denis Noble FRS, Department of Physiology, Anatomy, and Genetics, University of Oxford

Social bookmarking, RSS feeds and embedded video added to website

Wed, 18 Nov 2009 00:00:00 GMT

The NC3Rs website has undergone a programme of improvements which includes social bookmarking, RSS feeds and embedded video clips.

Working in partnership to advance the 3Rs in toxicity testing

Tue, 10 Nov 2009 00:00:00 GMT

Toxicological assessment of pharmaceutical and non-pharmaceutical chemicals is a regulatory requirement to ensure all compounds likely to be exposed to humans or the environment are safe. These studies rely on the use of large numbers of animals and involve a number of

New NC3Rs poster available

Wed, 2 Sep 2009 00:00:00 GMT

A poster highlighting the ways in which the NC3Rs works with scientists, animal technicians and veterinarians to drive advances in all three ‘Rs’ is now available.

Preclinical development of monoclonal antibodies: considerations for the use of non-human primates

Tue, 1 Sep 2009 00:00:00 GMT

The development of mAbs remains high on the therapeutic agenda for the majority of pharmaceutical and biotechnology companies. Often, the only relevant species for preclinical safety assessment of mAbs are non-human primates (NHPs), and this raises important scientific,

Human clearance prediction: shifting the paradigm

Tue, 1 Sep 2009 00:00:00 GMT

There is a growing momentum to use in vitro methods, nestled in in silico physiologically based pharmacokinetic models as the primary source of prediction of human clearance. This represents a shift in the paradigm for predictions in humans, which has

European Commission / European cosmetic industry research funding for alternatives to animal testing

Mon, 24 Aug 2009 00:00:00 GMT

In a unique joint effort, the European cosmetic industry has decided to match research funds made available by the European Commission under the 7th RTD Framework Programme.

ECVAM Scientific Advisory Committee - Open Call for expression of interest

Mon, 24 Aug 2009 00:00:00 GMT

The European Centre for the Validation of Alternative Methods (ECVAM), part of the European Commission Joint Research Centre, is renewing its Advisory Structure.

Application of toxicokinetics to improve chemical risk assessment: implications for the use of animals

Fri, 7 Aug 2009 00:00:00 GMT

While toxicokinetics has become an integral part of pharmaceutical safety assessment over the last two decades, its use in the chemical industry is relatively new. However, it is recognised as a potentially important tool in human health risk assessment and recent initi

Funding for alternatives to animal research nearly doubles compared to previous year

Wed, 29 Jul 2009 00:00:00 GMT

Funding of £4.5 million for 13 new projects that aim to replace, reduce or refine the use of animals in research and testing was announced today (29 July 2009) by the NC3Rs.

New Board Members announced

Mon, 20 Jul 2009 00:00:00 GMT

Three new members have been appointed to join the NC3Rs Board. Dr Phil Botham, Professor Jamie Davies and Mr Neil Yates will serve on the Board for three year terms from 15 July 2009.

Less is more: reducing the reliance on animal models for nausea and vomiting research

Wed, 1 Jul 2009 00:00:00 GMT

Animals have been used as experimental models for centuries and their use has enabled researchers to make significant advances in many areas of human health and disease. However, this is not always the case and there are limitations in using animal models as surrogates

Engineering tissue alternatives to animals: applying tissue engineering to basic research and safety testing

Wed, 1 Jul 2009 00:00:00 GMT

The focus for the rapid progress in the field of tissue engineering has been the clinical potential of the technology to repair, replace, maintain or enhance the function of a particular tissue or organ. However, tissue engineering has much wider applicability in basic

Opportunities for the replacement of animals in the study of nausea and vomiting

Wed, 1 Jul 2009 00:00:00 GMT

Nausea and vomiting are among the most common symptoms encountered in medicine as either symptoms of disease or side effects of treatments. Developing novel anti-emetics and identifying emetic liability in novel chemical entities rely on models that can recreate the com

Are acute toxicity studies required to support overdose for new medicines?

Sat, 27 Jun 2009 00:00:00 GMT

Our recent evidence-based review of the requirement for acute toxicity studies in pharmaceutical drug development demonstrated that acute toxicity studies are not useful to support the first clinical trial in humans (Robinson et al., 2008). Additional analysis of our da

New leaflet highlights benefits of the 3Rs

Wed, 24 Jun 2009 00:00:00 GMT

The NC3Rs has produced a new leaflet which explains what the 3Rs are, and how they can benefit science, innovation and animal welfare.

An improved containment system for experimentally infected macaques

Thu, 18 Jun 2009 00:00:00 GMT

Dr Mike J Dennis, Health Protection Agency, Centre for Emergency Preparedness and Response

Nanotechnology: applying the 3Rs to risk assessment

Thu, 18 Jun 2009 00:00:00 GMT

Dr Barry Park, Oxonica & Dr Patricia Martin, Product Assessment and Regulatory Compliance

Moving 'Beyond animal research' with virtual twin experimentation

Thu, 4 Jun 2009 00:00:00 GMT

After challenging New Scientist magazine readers to articulate how scientific advances could do away with animal research, a judging panel has chosen a winner.

Automated blood sampling and the 3Rs

Tue, 5 May 2009 00:00:00 GMT

Ann Holmberg, DiLab AB, and Robert Pelletier, DiLab Inc.

Assuring consumer safety without animals: applications for tissue engineering

Wed, 1 Apr 2009 00:00:00 GMT

Humans are exposed to a variety of chemicals in their everyday lives through interactions with the environment and through the use of consumer products. It is a basic requirement that these products are tested to assure they are safe under normal and reasonably foreseea

Refinements in husbandry, care and common procedures for non-human primates

Wed, 1 Apr 2009 00:00:00 GMT

This report produced by the British Veterinary Association Animal Welfare Foundation (BVAAWF)/Fund for the Replacement of Animals in Medical Experiments (FRAME)/Royal Society for the Prevention of Cruelty to Animals (RSPCA)/Universities Federation for Animal Welfare (UF

Research showcased at Westminster event to mark the 3Rs anniversary

Thu, 26 Mar 2009 00:00:00 GMT

UK scientists showcased their latest work to replace, reduce and refine the use of animals in research and testing at an NC3Rs event held in the House of Lords yesterday (Wednesday 25 March)

New report on refining non-human primate care and use

Wed, 25 Mar 2009 00:00:00 GMT

Ninth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement

NC3Rs seeking new Board Members

Wed, 25 Mar 2009 00:00:00 GMT

Candidates should be respected individuals with a proven track record in relevant research and display a commitment to the development of all three 'Rs'

New guidance on sharing and archiving genetically altered mice

Wed, 11 Mar 2009 00:00:00 GMT

The RSPCA, MRC, Cancer Research UK, BBSRC and NC3Rs are launching new guidance in the form of a booklet aimed at scientists working with animals

Essay competition challenge to think beyond animal research

Thu, 5 Mar 2009 00:00:00 GMT

The head of the government-funded NC3Rs calls for futuristic ideas for reducing animal use over the next three decades

Botulinum toxin: applying the 3Rs to product potency testing

Thu, 5 Mar 2009 00:00:00 GMT

Dr Dorothea Sesardic and Dr Rose Gaines Das, National Institute for Biological Standards and Control

Alternatives to animals

Wed, 4 Mar 2009 00:00:00 GMT

How long will it be before we can wave goodbye to experiments involving animals? This question, which causes more antagonism than just about any other issue in science, is about to come to a head again: after 23 years, the European Union legislation governing the use of

Prize for replacing animal use in sight-saving research

Wed, 28 Jan 2009 00:00:00 GMT

The winners of the 3Rs prize for 2008 are Dr Martin and Mr Johnson

New video clips on blood sampling from rodents

Thu, 8 Jan 2009 00:00:00 GMT

Four new video clips have been added to the NC3Rs Blood Sampling Microsite, to assist with staff training. A fifth is available on request.

New DVD on training laboratory primates

Thu, 27 Nov 2008 00:00:00 GMT

A DVD titled 'Training laboratory primates' has been produced by EUPRIM-Net, an EU-funded network of eight primate research centres.

Investment in alternatives to animal research rises for fifth consecutive year

Thu, 11 Sep 2008 00:00:00 GMT

The NC3Rs has announced funding of £2.6 million for ten new projects that aim to replace, reduce or refine the use of animals in research and testing.

Home Office publishes statistics on the use of animals in scientific procedures in 2007

Mon, 21 Jul 2008 00:00:00 GMT

The number of procedures carried out in 2007 was just over 3.2 million, a rise of approximately 6 per cent (189,500) on 2006.

New NC3Rs Board Chair is Professor Ian Kimber

Wed, 9 Jul 2008 00:00:00 GMT

Professor Ian Kimber, University of Manchester, has been appointed as the new Chair of the Board of the NC3Rs.

NHMRC guidelines on the assessment and alleviation of pain and distress in research animals

Mon, 30 Jun 2008 00:00:00 GMT

Although primarily to be used by investigators and members of Animal Ethics Committees in Australia, the new Guidelines are relevant to those conducting, reviewing and managing research with animals elsewhere in the World.

Intelligent testing strategies in ecotoxicology

Wed, 18 Jun 2008 00:00:00 GMT

Professor Tom Hutchinson, Plymouth Marine Laboratory

Major UK funders publish common rules for animal research

Thu, 8 May 2008 00:00:00 GMT

Five of the UK's major funders of animal research today published common guidelines for using animals in research.

NC3Rs seeking new Board Chair

Wed, 13 Feb 2008 00:00:00 GMT

The NC3Rs is a scientific organisation at the forefront of applying the 3Rs (Replacement, Reduction and Refinement) to the use of animals in research in the biosciences.

A double win – tackling developing world disease and reducing use of animals in research

Wed, 16 Jan 2008 00:00:00 GMT

The winner of the third annual 3Rs Prize is Dr Charlotte Gower

Use of thousands of animals avoided as test proved redundant

Tue, 8 Jan 2008 00:00:00 GMT

Important step taken to reduce animals used in specific safety test for new medicines

Cefic-LRI and EUROTOX Innovative Science Award

Thu, 20 Dec 2007 00:00:00 GMT

Details €100,000 prize and invitation for grant applications

The LifeShirt PreClinical System is a significant advance towards answering the call of the 3Rs

Wed, 12 Dec 2007 00:00:00 GMT

Dr P. Alexander Derchak, VivoMetrics Inc.

Government funding for NC3Rs to more than double

Mon, 10 Dec 2007 00:00:00 GMT

Ian Pearson, Minister of State for Science and Innovation has announced that funding for the NC3Rs is set to more than double over the next three years.

A European pharmaceutical company initiative challenging the regulatory requirement for acute toxicity studies in pharmaceutical drug development

Wed, 5 Dec 2007 00:00:00 GMT

Regulatory guidelines indicate acute toxicity studies in animals are considered necessary for pharmaceuticals intended for human use. This is the only study type where lethality is mentioned as an endpoint. The studies are carried out, usually in rodents, to support mar

Cash boost for increased investment in 3Rs research

Wed, 19 Sep 2007 00:00:00 GMT

Ian Pearson, Minister for Science and Innovation announces £2.4m for 11 new 3Rs projects

Validating refinements to laboratory housing: asking the animals

Thu, 30 Aug 2007 00:00:00 GMT

Dr Chris M Sherwin, Centre for Behavioural Biology, Department of Clinical Veterinary Science, University of Bristol

Researchers to be surveyed for views on replacing use of animals

Mon, 23 Jul 2007 00:00:00 GMT

The aim of the survey is to find out what researchers know about the 3Rs in animal research and how relevant they are to their daily working lives.

Lord Turnberg stands down as Chair of the NC3Rs Board

Wed, 18 Jul 2007 00:00:00 GMT

The process of appointing a successor is currently underway and the Deputy Chair, Professor Paul Flecknell, will fulfil the duties of the Chair until an appointment has been made.

Initiative to improve genotoxicity assays and reduce animal use

Fri, 6 Jul 2007 00:00:00 GMT

A European collaborative project to improve the accuracy of the in vitro tests used to predict the cancer-causing potential or 'carcinogenicity' of compounds such as pharmaceutical medicines is being initiated by Covance, with funding from the NC3Rs and ECVAM.

Identifying laboratory rodents using earprints

Thu, 5 Jul 2007 00:00:00 GMT

Mr Jens Cameron, DiLab, Sweden; Dr Christina Jacobson, AstraZeneca R&D, Sweden; Dr Kenneth Nilsson, Halmstad University, Sweden; Professor Thorsteinn Rögnvaldsson, Halmstad University, Sweden

Response to Weatherall Report on primate use

Tue, 12 Jun 2007 00:00:00 GMT

The NC3Rs welcomes the endorsement for the work being done by the NC3Rs, but is disappointed that the report does not go far enough in mapping priorities.

Challenging the requirement for acute toxicity studies – workshop report published

Fri, 11 May 2007 00:00:00 GMT

As part of a collaboration between the NC3Rs and the European pharmaceutical industry a working group of 15 international companies have been sharing and analysing the value of data from single dose rodent acute toxicity studies.

Can animals be replaced in the study of a multi-system reflex?

Thu, 12 Apr 2007 00:00:00 GMT

NC3Rs is embarking on an ambitious and exciting project to review the use of animals in nausea and emesis research.

Zebrafish as an alternative model organism for disease modelling and drug discovery: implications for the 3Rs

Wed, 21 Mar 2007 00:00:00 GMT

Dr Angeleen Fleming, Cambridge Institute for Medical Research

Scientists impress MPs with work to minimise the use of animals

Fri, 9 Mar 2007 00:00:00 GMT

Researchers who were most successful in communicating their 3Rs research to Parliamentarians at a showcase event in Portcullis House, were awarded prizes of £2k.

Voiceless Eureka Prize for research which replaces the use of animals or animal products

Fri, 9 Mar 2007 00:00:00 GMT

The Voiceless Eureka Prize for Research which Replaces the Use of Animals or Animal Products is sponsored by the Sherman Foundation.

The Humane Society of the United States presents the 2007 Russell and Burch Award

Tue, 20 Feb 2007 00:00:00 GMT

The award is designed to recognise individual scientists who have made significant changes or improvements in how animals are utilised in the laboratory.

Use of primates in drug testing could be reduced

Mon, 5 Feb 2007 00:00:00 GMT

Use of primates in the safety testing of monoclonal antibodies prior to clinical trials could be reduced by the wider application of existing technologies, according to a paper published in the February issue of Nature Reviews Drug Discovery.

NC3Rs Blood Sampling Microsite launched

Fri, 2 Feb 2007 00:00:00 GMT

To assist with refinement of blood sampling, the NC3Rs has launched a Blood Sampling Microsite

Refinement of rodent research through environmental enrichment and systematic randomization

Fri, 2 Feb 2007 00:00:00 GMT

Professor Dr Hanno Würbel, Division of Animal Welfare and Ethology, Justus-Liebig-University of Giessen; Dr Joseph P. Garner, Animal Sciences, Purdue University

Training laboratory-housed non-human primates, part 1: a UK survey

Thu, 1 Feb 2007 00:00:00 GMT

Training using positive reinforcement is increasingly recognised as a valuable tool for the humane and effective management and use of laboratory-housed non-human primates. We utilised a mixed-mode questionnaire to survey use of training and other learning processes (so

Preclinical safety testing of monoclonal antibodies: the significance of species relevance

Thu, 1 Feb 2007 00:00:00 GMT

Selecting a pharmacologically relevant animal species for testing the safety and toxicity of novel monoclonal antibody (mAb) therapies to support clinical testing can be challenging. Frequently, the species of choice is the primate. With the increased number of mAbs in

Prize for improving welfare of hamsters used in medical research

Tue, 23 Jan 2007 00:00:00 GMT

The winner of the second annual 3Rs Prize is Professor Alan Fairlamb.

The FELASA Award - a major new award for laboratory animal science within Europe

Thu, 14 Dec 2006 00:00:00 GMT

FELASA has established a triennial Award to recognise and reward a defined piece of original scientific work.

Showcasing the 3Rs in Parliament

Fri, 27 Oct 2006 00:00:00 GMT

The NC3Rs will be holding a poster event in Westminster on 28 February 2007 to showcase the latest examples of 3Rs research for MPs, Peers and other important stakeholders.

Science and the 3Rs – a joint NC3Rs/ Biosciences Federation symposium

Fri, 27 Oct 2006 00:00:00 GMT

The NC3Rs in partnership with the Bioscience Federation's Animal Sciences Group is hosting a one-day symposium.

The Slug Mucosal Irritation assay: an alternative assay for local tolerance testing

Mon, 11 Sep 2006 00:00:00 GMT

Dr Els Adriaens, Lab Pharmaceutical Technology, Ghent University

Report of CO₂ euthanasia meeting published

Fri, 11 Aug 2006 00:00:00 GMT

Carbon dioxide (CO2) is one of the most commonly used methods of rodent euthanasia.

Co-developer of the 3Rs concept dies aged 81

Fri, 4 Aug 2006 00:00:00 GMT

Professor William Russell, who originally developed the concept of the 3Rs with his colleague Rex Burch, sadly died on 27 July 2006 at the age of 81.

Re-using cow eyes to help replace animal tests

Mon, 31 Jul 2006 00:00:00 GMT

A proposal to re-use cow eyes left over as abattoir waste, as a replacement for animal tests, is one of nine projects that have been awarded funding by the NC3Rs

Home Office Animal Statistics for 2005 show small rise

Mon, 24 Jul 2006 00:00:00 GMT

The Home Office has announced the publication of the 2005 annual statistics on animal research.

Finding new homes for ex-laboratory and surplus zoo primates

Sat, 1 Jul 2006 00:00:00 GMT

This article is written to assist organizations which may be considering "rehoming" primates and draws upon the experience of members of the Primate Society of Great Britain (PSGB) Captive Care Working Party. Rehoming ex-laboratory and surplus zoo primates is

2006 European Animal Welfare and Alternatives Awards

Wed, 14 Jun 2006 00:00:00 GMT

Applications are now being accepted for the 2006 European Animal Welfare and Alternatives Awards.

New CD-ROM on humane endpoints

Tue, 13 Jun 2006 00:00:00 GMT

A CD-ROM entitled 'Humane endpoints in laboratory animal experimentation' has been produced through an initiative of the Netherlands Association for Laboratory Animal Science (NVP).

Recent papers - Non-invasive imaging of animals

Wed, 10 May 2006 00:00:00 GMT

To keep you up to date on some of the latest work with implications for the 3Rs being published

An update on the Innovative Medicines Initiative and its implications for the 3Rs

Fri, 5 May 2006 00:00:00 GMT

Dr Ian Ragan, CIR Consulting Ltd.

3Rs studies considered for DTI Safety Biomarker funding

Mon, 3 Apr 2006 00:00:00 GMT

Research into safety biomarkers may have implications for the 3Rs (reduction, refinement and replacement of animals in research).

Assessing the welfare of genetically altered mice

Sat, 1 Apr 2006 00:00:00 GMT

In 2003, under the auspices of the main UK funders of biological and biomedical research, a working group was established with a remit to review potential welfare issues for genetically altered (GA) mice, to summarize current practice, and to recommend contemporary best

Grants for refinements of animal studies available

Mon, 27 Mar 2006 00:00:00 GMT

The ECLAM/ESLAV Foundation is a charitable organisation that funds studies for the discovery, validation and implementation of refinement of the care and use of animals in research.

Recent papers - Tissue engineering and cell cultures

Fri, 10 Mar 2006 00:00:00 GMT

To keep you up to date on some of the latest work with implications for the 3Rs being published

Refinement benefits animal welfare and quality of science

Wed, 1 Mar 2006 00:00:00 GMT

Professor Merel Ritskes-Hoitinga, FELASA President, Radboud University Nijmegen Medical Centre; Line Bjoerndal Gravesen, University of Southern Denmark; Inger Marie Jegstrup, University of Southern Denmark

Microdosing and the 3Rs

Wed, 8 Feb 2006 00:00:00 GMT

Professor Malcolm Rowland, University of Manchester

Inaugural prize given for improving animal welfare in research

Wed, 25 Jan 2006 00:00:00 GMT

A researcher's innovative approach to refining medical research on animals has been awarded the inaugural Replacement, Refinement and Reduction (3Rs) Prize.

Primate sensory capabilities and communication signals: implications for care and use in the laboratory

Tue, 6 Dec 2005 00:00:00 GMT

Dr Mark Prescott, NC3Rs

Training laboratory-housed non-human primates, part 2: resources for developing and implementing training programmes

Thu, 1 Dec 2005 00:00:00 GMT

Positive reinforcement training is increasingly being used to refine scientific, veterinary and husbandry procedures involving laboratory-housed non-human primates and to enhance primate care and wellbeing. However, there is a need and demand for greater access to resou

Harmonising the definition of refinement

Tue, 1 Nov 2005 00:00:00 GMT

Russell and Burch's Three Rs (replacement, reduction and refinement) remain the cornerstone for principles guiding humane experimental research. However, the concept of refinement has evolved considerably since its first inception and there have been numerous interpreta

Bursary available to attend TestSmart DNT symposium in March 2006

Fri, 28 Oct 2005 00:00:00 GMT

Any UK delegate who has submitted a poster to this symposium will be eligible to enter for the bursary which will cover registration, accommodation, travel and subsistence (up to £2k in total per delegate).

Making sense of scents: reducing aggression and uncontrolled variation in laboratory mice

Tue, 30 Aug 2005 00:00:00 GMT

Professor Jane Hurst, Department of Veterinary Clinical Science, University of Liverpool

Biophotonic imaging and the reduction of animal usage in experimental research

Mon, 25 Jul 2005 00:00:00 GMT

Dr Kevin P Francis, Xenogen Corporation

£1million for new projects to replace, refine and reduce animal experiments

Wed, 6 Jul 2005 00:00:00 GMT

The NC3Rs today announces new grants for pioneering research projects.

Mutation induction in mice: reduction in practice

Fri, 10 Jun 2005 00:00:00 GMT

Dr Yuri E Dubrova, Department of Genetics, University of Leicester

The NC3Rs announces increased funding for the 3Rs and welcomes the Nuffield Council report

Wed, 25 May 2005 00:00:00 GMT

The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) announces today that it has been awarded additional money from the Government.

Pharmaceutical industry backs 3Rs centre with sponsorship of new post

Thu, 27 Jan 2005 00:00:00 GMT

A three-year sponsorship of a new scientific post at the NC3Rs that demonstrates the pharmaceutical industry's continued commitment to the centres objectives has been announced by the ABPI.

Guidance on the transport of laboratory animals: report of the Transport Working Group established by the Laboratory Animal Science Association (LASA)

Sat, 1 Jan 2005 00:00:00 GMT

These guidelines define the general principles to be observed when transporting rodents, rabbits, ferrets, dogs, cats, nonhuman primates, minipigs and amphibians including Xenopus for use as laboratory animals. This is an international document and the Group is aware th

The NC3Rs announces new funds and research projects to advance the 3Rs

Mon, 27 Sep 2004 00:00:00 GMT

The first actions of the newly appointed Board of the NC3Rs are announced today.