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NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

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173 results

Guidance, information and recommendations for those working with zebrafish.

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The positive impact playpens have on laboratory rat welfare, and guidance on how to set one up in your institution.

A tall cage which has been used to create a rat playpen. There are three different tiers with ladders to allow the rats to climb up between each one. A number of white rats can be seen moving between the different levels. Enrichment and play objects are available on each level including an cardboard box that used to hold laboratory gloves, coloured balls, tubes, a wheel and a raised platform on the top level with some bedding material.

Reducing and refining acute toxicity tests in the pharmaceutical and chemicals industries.

A white mouse on a technician's gloved hands

Providing an evidence base to refine and reduce the use of vertebrates in (regulatory) ecotoxicology studies

A group of young rainbow trout

Using exposure science to refine and reduce animal use, and support the uptake of new approach methodologies

A lister hooded rat (black head white body) seen in a standard rat housing cage. The rat is standing on a plastic box and is looking out of the open cage lid.

Guiding strategy and encouraging the adoption of microsampling techniques within any research or safety study.

A brown and white rat in the gloved hands of an animal technician.

Guidance on reducing or refining animal use for studies with cardiovascular, central nervous system and respiratory functional measurements.

A beagle at an indoor play area

Quarterly e-newsletter to keep the scientific community updated on news from the NC3Rs Toxicology and Regulatory Sciences programme.

A white icon of an envelope on a purple background.

Information and resources on malocclusion in mice to improve welfare within a research setting.

One mouse exhibiting healthy teeth and another exhibiting unhealthy, maloccluded teeth

A video resource for introductory training on the 3Rs aimed at in vivo researchers and animal technicians.

Cover slide for the 3Rs training webinar. The title of the talk is seen in white text on a blue background - The 3Rs: Their definition, application and importance to your work.