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International 3Rs Prize now open for applications. £30k prize (£2k personal award) for outstanding science with demonstrable 3Rs impacts.

NC3Rs | 20 Years: Pioneering Better Science

Search our 3Rs resource library

Use the filters below to narrow down our resources to those relevant to your role, the model you are interested in, or by topic area. Filters are best used by combining two or more to narrow down the results.

107 results

Guidance, information and recommendations for those working with zebrafish.

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Practical advice on calculating how many matings to set up, including available breeding calculator tools.

A mouse illustration with maths symbols and numbers

A high level introduction to best practice in mouse colony management, including confirming, archiving and maintaining mouse strains.

White icons of a magnifying glass focused on a mouse, on a blue background

Guidance on the role of the 3Rs Champion within the research community.

A white trophy with the term '3Rs' on it sits on a bright yellow background.

Projects to ensure that the in vivo tests involved in ED assessment are as robust as possible, particularly focusing on aquatic species.

Zebra fishes in tank

Information on techniques for sampling blood in the mouse, covering non-surgical, surgical and terminal techniques.

Black mouse standing on a gloved finger, with an icon of a needle and syringe on a yellow background in the corner of the image.

How funding bodies can embed the 3Rs in their peer review process, including details of our review and advice service.

Icon representing peer review: two people connected by arrows going round a paper
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A series of video tutorials to develop skills in the administration of substances and apply best practice in aseptic surgical techniques in rodents.

A white mouse on a technician's gloved hands

Archiving can provide a back-up to production colonies, minimise genetic drift, reduce the need for tick-over colonies and preserve valuable models.

A white sperm and egg icon on a blue background