Registration now open
Showcasing 12 years of research supported through the 3Rs Prize and the announcement of the 2017 prize winner.
Apply now for our vacancies
We are currently recruiting for a number of exciting roles within our organisation.
Cardiovascular Showcase event (23 March 2018)
The event will highlight NC3Rs-funded work and engage the wider research community.
Highlight notice 2018: across all funding schemes
Applications incorporating systematic reviews for 3Rs purposes
Public engagement awards scheme: open rolling call
Grant holders can apply for an award of up to £1,500 to engage the public in 3Rs research.
New standards for non-human primate research
We have launched an updated version of our guidelines on accommodation, care and use.
2017: The Year of Laboratory Rodent Welfare
Look back at our year of activities focusing on the welfare of rats and mice used in research.
Re-use of needles: is this an indicator of a culture of care?
This guest blog post explores the issue of re-using needles in day-to-day practice.
Collecting DNA from zebrafish
New project explores a non-invasive DNA collection technique, improving fish welfare.
The 3Rs
We have updated our definitions of the 3Rs so they are more reflective of contemporary scientific practice and developments.
IMPROVE-ing animal welfare in stroke research
New NC3Rs guidelines for best practice in the care and use of rodent models of stroke.
Approaches to monkey chair restraint: survey findings
Recommendations for refining training and procedures.

The NC3Rs

If you are a scientist, animal technician, veterinarian, regulator, funder or policy maker, the NC3Rs can help you to:

  • Drive scientific and technological developments that replace, reduce or refine the use of animals in research (the 3Rs)
  • Ensure your animal experiments are as robust and reproducible as possible
  • Provide the best welfare for laboratory animals


Science-led and evidence-based, we fund research and early careers, foster collaborations between universities and industry to develop and commercialise 3Rs technologies, and provide information on the latest advances to put the 3Rs into practice.

Keep in touch

Latest news & blogs

£700k awarded in the 2017 CRACK IT Challenge competition

Seven teams have been awarded funding in the 2017 CRACK IT Challenge competition, which brings together large industries, academia and SMEs to deve

Fellowships awarded to support early career researchers

We have awarded four new NC3Rs Fellowships to support 3Rs research in a range of disease areas.

Meet the 'locals'! The NC3Rs Regional Programme Managers share their experience

Regional Programme Managers Kamar Ameen-Ali and Emma Stringer share their experience of working with universities to promote the 3Rs.

Tail handling reduces the value of reward in laboratory mice

Researchers at Newcastle University have found  picking up laboratory mice by the tail makes them less responsive to reward, indicating a more depressive-like state compared to mice handled using a tunnel.

Modelling bone formation and maturation in vitro

New model developed by researchers at the Universities of Birmingham and Oxford with NC3Rs funding.

New NC3Rs Board members appointed

We are pleased to announce that Professor Paul Garside, Dr David Lovell and Professor Jon Timmis have joined the NC3Rs Board.