10 years of CRACKing IT
Read about our programme of events celebrating our open innovation programme's first ten years.
Visit the ARRIVE 2.0 website
Find information and resources to improve the reporting of your in vivo research.
Listen to "3 Minute 3Rs"
A monthly podcast highlighting the latest 3Rs research, presented by Lab Animal, the North American 3Rs Collaborative and the NC3Rs.
NC3Rs webinars
Register for our upcoming webinars and watch recordings of past presentations on a wide range of 3Rs topics.
3Rs for the public
Learn more about the 3Rs and their importance in research.
The NC3Rs and the 3Rs during COVID-19
An update on what we are doing to support the research community.
Download the latest Tech3Rs
Our quarterly newsletter for animal technicians can help you discover new ways to put the 3Rs into practice in your facility.
Breeding and colony management
Guidance on re-establishing colonies following COVID-19 lockdown or any other interruption.
Animal technician hub
A range of resources to help animal care staff implement the 3Rs.
Experimental Design Assistant
A free online tool to help you design better experiments, using fewer animals and producing more robust and reproducible results.
Research culture and the 3Rs
Resources to help you strengthen the research culture of your group or institution through applying the 3Rs effectively.
Visit the NC3Rs gateway
Read detailed 3Rs method articles from our grant holders via our open access portal.

The NC3Rs: Pioneering better science


We help the research community use the latest science and technology to replace animal studies, providing new approaches for biomedical research and avoiding the time and cost associated with in vivo models. Where the use of animals is still required, we support researchers to design the best experiments so that their methods and findings are robust and reproducible. We provide information and guidance on the latest knowledge to improve laboratory animal welfare.


Find out more: About the 3Rs | About the NC3Rs

Keep in touch

Latest news

Meet our new Training Fellows

Four new awards will support early career researchers to prepare for an independent career in their chosen 3Rs field.

10 years of CRACKing IT

Celebrating 10 years of our challenge-led, milestone-driven funding competition, CRACK IT Challenges.

New NC3Rs Board members appointed

The five new members bring expertise in animal welfare, neurobiology, glycobiology, systems biology and in vitro toxicology.

ARRIVE guidelines 2.0 now available in six languages

The guidelines are now available in French, German, Chinese, Dutch, Portuguese and Italian.

3Rs citizen science project wins at the 7th Annual Openness Awards

Secret Lives of Mice, developed by MRC Harwell and the NC3Rs, was recognised for engaging the public in animal research.

Outstanding Technician of the Year awarded to John Waters

Congratulations to John, recognised at the THE awards for his work on non-aversive mouse handling methods.