The NC3Rs CRACK IT Challenges competition funds collaborative R&D to deliver marketable products or services for the bioscience sector to replace, reduce and refine their use of animals. Challenges are identified jointly by the NC3Rs and Sponsors who provide in-kind support and/or funding. Depending on the level of R&D required, Challenges can be single- or two-phase.
This year, up to £3.5 million funding is available to solve five Challenges that focus on delivering 3Rs, business and scientific impacts across diverse areas including wound healing, mouse welfare, animal-free reagents and in vitro immunology. The competition will open for applications in September.
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Interested in applying for one of this year’s Challenges?
We are hosting a series of webinars from 7 to 10 September to launch the 2020 CRACK IT Challenges competition. Each webinar will focus on a specific Challenge and will give you an opportunity to learn more about the competition, ask the Sponsors questions and find out how to submit a competitive application. Links to register for each webinar can be found below.
 Challenge 35: In vitro TDAR
A human immune response assay for the assessment of immune modulation
This two-phase Challenge aims to develop a human in vitro T-cell dependent antibody response (TDAR) assay to assess the immune enhancement properties of preclinical immunomodulatory therapeutics. This could reduce the number of non-human primates currently used for this purpose, as well as better predicting clinical outcomes.
Sponsors: Bayer AG, GSK and Merck Healthcare KGaA
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Register for webinar (Thursday 10 September, 2pm BST)
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