Systematic reviews in animal research: Launch of SyRF

  • NC3Rs
Thursday 30 March 2017
Central London

The NC3Rs in collaboration with the CAMARADES group is hosting a half-day seminar on systematic reviews in animal research. At this meeting we will launch the CAMARADES-NC3Rs Systematic Review Facility (SyRF) web app – a new free-to-use tool to help researchers perform systematic reviews and meta-analyses of animal studies.

Although these approaches are common practice in clinical research, they remain relatively under-utilised in animal research. Recent reviews have illustrated their potential for advancing the 3Rs, for example by supporting a reduction in animal numbers, determining whether high severity tests or multiple tests are necessary, and avoiding the use of uninformative models in animal research.

The aims of the meeting are:

  • To provide a short introduction to the application of systematic review and meta-analysis to animal research, including their importance for the 3Rs, knowledge translation and evaluating risks of bias.
  • To launch a new, free NC3Rs-funded web application "SyRF", which provides a platform to help researchers perform all stages of systematic review and meta-analysis.

The meeting will include:

  • Background to systematic review and meta-analysis.
  • Examples of contribution to the 3Rs, to knowledge translation and to evaluating risks of bias.
  • Potential role of machine learning and text and data mining to systematic review and meta-analysis.
  • Practical challenges encountered by those conducting systematic review and meta-analysis of data from animal studies and how the SyRF web application helps overcome these.
  • Demonstration of the SyRF web application.

The draft event programme is available here.

Who should attend?

The meeting is relevant to:

  • Researchers (e.g. PhD students, post docs and PIs) embarking on a research project who would like to start with a systematic summary of existing knowledge
  • Research users (e.g. AWERB members, NVSs or regulators) seeking robust evidence summaries to inform their decision making.
  • Those experienced in systematic reviews and meta-analysis who are interested in the use of novel tools.


Attendance is free, but registration is essential. The closing date for registration is 17 March 2017.

You will need an NC3Rs website account to register. Please use your institutional email address when registering.


Event status

Registration now closed