Work on an in silico model that predicts cardiotoxicity more accurately than animal studies has won the 2017 3Rs Prize, awarded by the NC3Rs and sponsored by GSK.
To celebrate International Women’s Day 2018, we are highlighting a number of female researchers at different career stages, including NC3Rs grant holders, whose fantastic work across a broad range of disciplines is helping advance the 3Rs in the UK
The NC3Rs has provided a peer review and advice service to the major UK funders of animal research for over a decade.
Seven teams have been awarded funding in the 2017 CRACK IT Challenge competition, which brings together industry, academia and SMEs to develop marketable products or improve business processes that will have a significant 3Rs impact.
Researchers at Newcastle University have found that picking up laboratory mice by the tail makes them less responsive to reward, suggesting a more depressive-like state compared to mice handled using a tunnel1. This finding adds to previous studies
In late 2016 the NC3Rs recruited two Regional Programme Managers, Dr Kamar Ameen-Ali and Dr Emma Stringer.
We are pleased to announce four new NC3Rs Fellowships, a commitment of just over £730,000, awarded to support 3Rs research in a range of disease areas.
Researchers from the Universities of Birmingham and Oxford, funded by the NC3Rs, have developed a new self-structuring model of bone tissue in vitro that can be used instead of experiments on live animals to study bone formation and maturation
We are pleased to announce that Professor Paul Garside, Dr David Lovell and Professor Jon Timmis have joined the NC3Rs Board.
2017 was a busy year for the NC3Rs – as well as being our Year of Laboratory Rodent Welfare, we undertook a number of initiatives to advance the 3Rs, forging new partnerships, developing guidelines for best practice and continuing to fund the
How rat tickling can improve welfare.
Previous research by Dr Mike Emerson at Imperial College London, funded by the NC3Rs, has developed a refined mouse model for studying thrombosis.
In this blog post, Dr Mark Prescott, Director of Policy and Outreach, and Dr Nathalie Percie du Sert, Head of Experimental Design and Reporting, reflect on their involvement in the recent 8th International Conference of the Laboratory Animal
Two recently published papers co-authored by NC3Rs staff members have explored the application of the 3Rs to research and safety testing involving non-human primates (NHPs).
Our recent guest blog post is from Dr Lucy Whitfield, Royal Veterinary College, and Dr Sally Robinson, AstraZeneca, who cover the topic of reusing hypodermic needles in day-to-day practice.
In the final blog of the ‘Data, data, data’ series*, Dr Manasi Nandi, Senior Lecturer in Integrative Pharmacology at King’s College London talks about her project as a case study where mathematical modelling can help advance the 3Rs by improved
A study recently published in Disease Models & Mechanisms describes a new approach for inducing stroke in mice that reduces variability in the experimental model.
Dr Peter Hohenstein from The Roslin Institute, University of Edinburgh and International Society for Transgenic Technologies, shares his impressions from the 14th Transgenic Technology Meeting (TT2017) which took place last month.
We have teamed up with LabAnimal and the North American 3Rs Collaborative to bring you “3 Minute 3Rs”, a new monthly podcast summarising the latest research and news in 3Rs science and technology.
Researchers from the University of Edinburgh have developed a new system to study Creutzfeldt-Jakob disease (CJD) in vitro.