Training and teaching resources to underpin implementation of refinement of in vivo studies Principal Investigator: Professor Paul Flecknell Newcastle University Infrastructure grant
Reducing the number of non-human primates in research by developing a rodent model of selective attention Principal Investigator: Dr Samuel Solomon University College London Pilot study grant
Finding effective analgesics in zebrafish by analysing effects on the nervous system (CNS) Principal Investigator: Professor Catherina Becker University of Edinburgh Pilot study grant
Live imaging of mucosal and vascular inflammation in zebrafish in response to a high cholesterol diet Principal Investigator: Professor Margaret Dallman Imperial College London PhD Studentship
Using human pluripotent stem cell-derived cardiomyocytes to test drug cardiac toxicity Contractor: Dr Tamer Mohammed CRACK IT Solution
Using C. elegans to produce proteins from parasitic nematodes for research and therapeutic use Principal Investigator: Dr David Weinkove Durham University Pilot study grant
Signalling pathways of leukocyte migration in silico Principal Investigator: Dr Juliane Liepe Imperial College London Fellowship
An integrative Dictyostelium, C. elegans and zebrafish approach to assess DART Contractor: Professor Raymond Peters, Institute for Risk Assessment Sciences/ Toxicology, U… CRACK IT Challenge
Live real-time imaging of life-threatening invasive fungal infections Principal Investigator: Dr Donna MacCallum University of Aberdeen Pilot study grant
Investigating tuberculosis by engineering human granulomas Principal Investigator: Dr Liku Tezera University of Southampton Pilot study grant
Development of computational models of bone formation and resorption to predict changes in bone in preclinical intervention studies Principal Investigator: Dr Ilaria Bellantuono University of Sheffield Project grant
Assessing cumulative severity in macaques used in neuroscience research Principal Investigator: Professor Melissa Bateson Newcastle University Project grant
Imprecision and importance: Probabilistic graphical models in toxicology Principal Investigator: Dr Jonathan Pitchford University of York Strategic grant
Quantifying the behavioural and facial correlates of pain in laboratory macaques Principal Investigator: Dr Sarah-Jane Vick University of Stirling Project grant
An early screen for emetic liability of NCEs using the amoeba Dictyostelium Contractor: Professor Robin Williams CRACK IT Solution
Uncertainty and confidence in applying mathematical models and in vitro data in toxicological safety assessments Principal Investigator: Dr John Gosling University of Leeds Strategic grant
An integrated platform to assay melanoblast and melanoma invasion of epidermis in vitro Principal Investigator: Dr Richard Mort University of Edinburgh PhD Studentship
Structural identifiability and indistinguishability analysis as tools for quantitative and systems pharmacology to support the 3Rs Principal Investigator: Dr Michael Chappell University of Warwick Strategic grant