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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

Activity type

Topic

Model

538 results

Improving preclinical proton radiation dosimetry using a biologically relevant murine dosimetry phantom

Principal Investigator: Miss Emma Biglin University of Manchester

Fellowship

Rows of PCR tubes on a yellow background

Embryonic zebrafish models of HACD1-deficiency to replace mammals in congenital myopathy and lipidomic research

Principal Investigator: Dr Gemma Walmsley University of Liverpool

PhD Studentship

High fidelity computational approaches to exploit new structures of cardiac ion channels

Principal Investigator: Dr Andrew Leach University of Manchester

PhD Studentship

Investigation of dopamine transporter dysfunction linked to DAT/SLC6A3 mutations in CRISPR-Cas engineered C. elegans and patient derived iPCSs

Principal Investigator: Dr Eva Kevei University of Reading

PhD Studentship

Modulating Macrophage Phenotypes During Infection In Zebrafish

Principal Investigator: Dr Phillip Elks University of Sheffield

PhD Studentship

Ensuring humane deaths for laboratory birds

Principal Investigator: Dr Jessica Martin University of Edinburgh

PhD Studentship

Refining mouse glucose homeostasis assessments

Principal Investigator: Professor Kate Ellacott University of Exeter

Skills and Knowledge Transfer grant

Local immunosuppression to improve the welfare of animals in neural transplantation experiments

Principal Investigator: Dr Victoria Roberton University College London

Skills and Knowledge Transfer grant

A stock image of round glass dishes containing blue and green liquid arranged closely together.

Developing a stem-cell prostate organoid model - reducing global animal usage in prostate development and cancer studies

Principal Investigator: Dr Adriana Buskin Newcastle University

Fellowship

Developing gene editing technologies in the non-mammalian infectious disease model organism, Galleria mellonella

Principal Investigator: Mr James Pearce University of Exeter

Fellowship

Long-term, self-maintaining primary 3D cultures of mouse and human epithelial tissues for reduction and replacement of animals in research

Principal Investigator: Dr David Fernandez-Antoran University of Cambridge

Skills and Knowledge Transfer grant

The application of trabecular bone organoids to investigate mineral-sensing in skeletal physiology and disease

Principal Investigator: Dr Alexandra Iordachescu University of Birmingham

Skills and Knowledge Transfer grant

Characterisation of Galleria mellonella innate immune response to Mycobacterium tuberculosis infection

Principal Investigator: Mr Masanori Asai Imperial College London

Fellowship

An orange Eppendorf rack partly full of PCR tubes.

Refinement of pre-exposure programs to reduce the use of fish in proliferative kidney disease monitoring in aquaculture

Principal Investigator: Dr Hanna Hartikainen University of Nottingham

PhD Studentship

Modelling of thrombus dynamics in a microfluidic 'vasculature'

Principal Investigator: Dr Nicola Mutch University of Aberdeen

PhD Studentship

Portrait of Dr Whyte and Professor Mutch

Drosophila based screening to replace mammalian systems to identify the functional role of candidate genes in controlling muscle dyadic architecture

Principal Investigator: Professor Andrew Trafford University of Manchester

PhD Studentship

Exploring the role of matrix encapsulation on early developmental decisions using non-animal sourced hydrogels

Principal Investigator: Professor Cathy Merry University of Nottingham

PhD Studentship

3D patient-derived organoids: A viable and complementary model to study neural system dysfunction in Alzheimer's Disease

Principal Investigator: Dr Marc Busche University College London

PhD Studentship

Efficacy of artificial imprinted antibodies in driving unwarranted immune responses

Principal Investigator: Dr Shoba Amarnath Newcastle University

PhD Studentship

Human stem cell models of de novo tumorigenesis to replace the use of animals for the study of cancer initiation

Principal Investigator: Dr Cinzia Allegrucci University of Nottingham

PhD Studentship