Development of novel imaging agents for the prospective quantification of joint damage to reduce animal numbers in osteoarthritis research Principal Investigator: Professor Tonia Vincent University of Oxford Project grant
Refining the mouse model of footpad immunisation and infection Principal Investigator: Dr Owain Millington University of Strathclyde Pilot study grant
Mechanisms of intestinal epithelial responses to inflammatory modulators Principal Investigator: Professor Inke Nathke University of Dundee Project grant
Development of human ex vivo bone-tumour niche for the study of cancer bone disease Principal Investigator: Dr James Edwards University of Oxford Pilot study grant
Real-time monitoring techniques and simplistic platelet assays to reduce and refine animal use in cardiovascular and respiratory biomedical research Principal Investigator: Dr Michael Emerson Imperial College London Project grant
Motor neuron regeneration in larval zebrafish Principal Investigator: Professor Catherina Becker University of Edinburgh PhD Studentship
Exploitation of an ex vivo disease model to characterise early events in retinal degeneration Principal Investigator: Dr J. Arjuna Ratnayaka University of Southampton PhD Studentship
Targeted, radiolabelled near-infrared quantum dots for high sensitivity and resolution, dual modality imaging of human tumours in mice Principal Investigator: Dr Anna Grabowska University of Nottingham Strategic grant
Determining the source of variability within experimental stroke models Principal Investigator: Dr Claire Gibson University of Leicester Pilot study grant
A novel product for reducing animal numbers in the production of transgenic mice Contractor: Ostara Biomedical Ltd CRACK IT Solution
Developing molecular therapies for glaucoma using an ex vivo human organ culture system Principal Investigator: Professor Colin Willoughby University of Liverpool PhD Studentship
Towards engineering a multi-cell lineage multi-organism intestine Principal Investigator: Dr Marc Veldhoen Babraham Institute Cambridge PhD Studentship
3D gene knockout tissue models using adult human stem cells Principal Investigator: Professor Paul Genever University of York PhD Studentship
DM-MAP: drug and metabolite microsampling analytical platform for preclinical medicines development Principal Investigator: Dr Darragh Murnane University of Hertfordshire PhD Studentship
Development of a non-mammalian, pre-clinical screening tool (FETOX) for predictive analysis of drug safety Principal Investigator: Dr Grant Wheeler University of East Anglia PhD Studentship
Development of a refined model of neuropathic pain: a model without frank nerve injury Principal Investigator: Dr Andrew Dilley University of Sussex PhD Studentship
Development of a method for non-lethal sampling from individual fish to investigate host responses to ectoparasites Principal Investigator: Professor Chris Secombes University of Aberdeen PhD Studentship
Non-invasive real-time bioluminescence imaging in living mice to interrogate transcription factor activity and fate of engrafted stem cells Principal Investigator: Dr Tristan McKay Manchester Metropolitan University Strategic grant
Ultrasound mediated bioluminescence tomography for high sensitivity, high spatial resolution 3D imaging Principal Investigator: Professor Stephen Morgan University of Nottingham Strategic grant
Molecularly Imprinted Nanoparticles (MIP NPs) as non-animal antibodies substitutes for detection of viruses Principal Investigator: Dr Alessandro Poma University College London Fellowship