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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

Activity type

Topic

Model

533 results

Development of a patient derived cellular model of circadian disruption in bipolar disorder

Principal Investigator: Dr Sridhar Vasudevan University of Oxford

PhD Studentship

Contribution of autophagy to the maintenance, invasion and metastasis of melanoma stem-like sub populations.

Principal Investigator: Dr David Hill Newcastle University

Fellowship

Find the target of valproic acid: pioneering the use of a non-animal model for basic biomedical (epilepsy) research

Principal Investigator: Professor Robin Williams Royal Holloway University of London

PhD Studentship

Professor Robin Williams holding up a beaker in woodlands

Developing microfluidic systems for high throughput studies of functional neuronal networks

Principal Investigator: Dr Michele Zagnoni University of Strathclyde

PhD Studentship

Reduction of use of experimental mice in type 1 diabetes research through non-invasive, in vivo longitudinal imaging

Principal Investigator: Dr Maja Wallberg University of Cambridge

Project grant

Developing an ethical, sustainable, human sensory neuron culture model for use in therapeutic pain research

Contractor: Professor Andrew Hart, NHS Greater Glasgow & Clyde

CRACK IT Challenge

Neon yellow lights on a black background

Labelled IMS TAG Proteins for Quantitative Mass Spectrometry Imaging

Principal Investigator: Professor Malcolm Clench Sheffield Hallam University

Strategic grant

Rows of PCR tubes on a yellow background

Generating zebrafish models of human eye movement disorders to replace mouse models

Principal Investigator: Dr Ivana Poparic King's College London

Fellowship

Creating an in vitro model of pathogenic ossification to explore methods for dispersion

Principal Investigator: Professor Liam Grover University of Birmingham

PhD Studentship

NephroScreen: toxicity screening with a human renal cell line in a perfused titerplate

Contractor: Northwestern Switzerland

CRACK IT Challenge

Human renal cell line in a perfused titerplate

Differentiating alveolar macrophage responses to inhaled medicines

Contractor: Dr Ben Forbes, Kings College London

CRACK IT Challenge

A multiscale model to minimise animal usage in Leishmaniasis drug development

Contractor: Professor Paul Kaye, University of York

CRACK IT Challenge

A blue circle surrounded by laptops in relation to sharing

Untangling tauopathies: A microfluidics based drug-screening platform for human tau mutation neurons

Contractor: Dr Selina Wray, University College London

CRACK IT Challenge

Engineered 2D & 3D hiPSC-CM platforms to detect cardiovascular safety liabilities

Contractor: Professor Chris Denning, University of Nottingham

CRACK IT Challenge

A green graphic of a heart with a pulse signal behind it.

Replacing rodent models for investigating the influence of the microbiome upon innate immune responses and resistance to pathogens

Principal Investigator: Dr Rachel Lawrence Royal Veterinary College

PhD Studentship

A 3D air-liquid interface airway epithelial cell model to study pathogen interactions within the bovine respiratory tract

Principal Investigator: Dr Robert Davies University of Glasgow

Project grant

A stock image of round glass dishes containing blue and green liquid arranged closely together.

SEARCHbreast: A virtual resource to facilitate sharing breast cancer materials and knowledge to benefit the 3Rs

Principal Investigator: Professor Valerie Speirs University of Leeds

Infrastructure grant

EFucci an atlas of proliferation to reduce mouse usage in embryonic proliferation assays

Principal Investigator: Dr Richard Mort MRC Human Genetics Unit University of Edinburgh

Pilot study grant

Dr Richard Mort with colleagues by a low wall with trees in the background

Towards an in vitro system of predictive biomarkers of in vivo liposome efficacy

Principal Investigator: Dr Andrew Devitt Aston University

Pilot study grant

Drosophila as a model to understand the role of glial cells in neurodegeneration

Principal Investigator: Dr Manolis Fanto King's College London

Project grant