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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

Activity type

Topic

Model

533 results

Neonatal BCG vaccination: screening for genetic factors that influence host-pathogen interactions and reducing and replacing the requirement for animal infection models in immune mechanism discovery

Principal Investigator: Professor Melanie Newport Brighton and Sussex Medical School

PhD Studentship

Using non-invasive in vivo imaging to address the 3Rs in high-throughput mouse phenotyping

Principal Investigator: Dr Mark Lythgoe University College London

PhD Studentship

Highly differentiated cultures of ferret airway epithelium for the study of respiratory viruses, including influenza

Principal Investigator: Professor Wendy Barclay Imperial College London

Project grant

Developing a platform of in vitro models of asthmatic and healthy lung: an alternative to the use of animals in asthma research

Principal Investigator: Dr Felicity Rose University of Nottingham

Strategic grant

A stock image of round glass dishes containing blue and green liquid arranged closely together.

FIGCS: An in vitro model to replace ecotoxicity testing of fish to pharmaceuticals

Principal Investigator: Professor Christer Hogstrand King's College London

Project grant

A chronic model of epilepsy in organotypic brain slice cultures of the rat entorhinal cortex

Principal Investigator: Professor Roland Jones University of Bath

Project grant

Reducing mouse number in complex genetic experiments

Principal Investigator: Dr Pieter Hohenstein University of Edinburgh

Project grant

A tissue engineered construct to monitor mucosal immunity in asthma

Principal Investigator: Professor Donna Davies University of Southampton

Strategic grant

Zebrafish behavioural assays to identify genetic mechanisms underlying drug seeking and addiction

Principal Investigator: Dr Caroline Brennan Queen Mary University of London

Project grant

Development of cell based assays as replacement assays for Botulinum toxins and antitoxins

Principal Investigator: Dr Dorothea Sesardic National Institute for Biological Standards and Control

Project grant

Using the Drosophila fly intestine to investigate Wnt targets in vivo

Principal Investigator: Dr Owen Sansom University of Glasgow

Project grant

Derivation of conditionally immortalised mouse DRG cell lines

Principal Investigator: Dr Mohammed Nassar University of Sheffield

Project grant

Development of in vitro assays to determine vaccine efficacy in fish

Principal Investigator: Professor Christopher Secombes University of Aberdeen

Project grant

Professor Chris Secombes standing with a large green fish tank behind him

Stem cell-derived cardiomyocytes for detection of cardiotoxicity in cancer therapeutics

Principal Investigator: Professor Sian Harding Imperial College London

Project grant

A 3D tissue model of breast morphogenesis for replacing animals in testing for endocrine disrupting substances

Principal Investigator: Professor Charles Vyvyan Howard University of Ulster

Project grant

Applying the 3Rs to liver fibrosis research

Principal Investigator: Professor Matthew Wright Newcastle University

PhD Studentship

The validation of defined genotoxic thresholds, leading to better in vitro risk assessments of carcinogenic potential

Principal Investigator: Professor Gareth Jenkins Swansea University

PhD Studentship

Taming anxiety and variation in laboratory mice

Principal Investigator: Professor Jane Hurst University of Liverpool

PhD Studentship

Refinement of rearing practices in marmosets

Principal Investigator: Professor Hannah Buchanan-Smith University of Stirling

PhD Studentship

An in vitro model system to assay kidney-pathogen interactions determining outcome of Candida albicans infection

Principal Investigator: Dr Donna MacCallum University of Aberdeen

PhD Studentship