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Office-led project
Grants
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- Strategic grant
- Skills and Knowledge Transfer grant
- Technologies to Tools grant
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CRACK IT
- CRACK IT Challenge
- CRACK IT Solution
Origin retinas syringe insertion device
Contractor:
Allen Pearson, Origin Product Design Limited
CRACK IT Challenge
NephroScreen: toxicity screening with a human renal cell line in a perfused titerplate
Contractor:
Dr Martijn Wilmer, Radboud University Medical Centre
CRACK IT Challenge
A miniature wireless EEG system for continuous monitoring of mice brainwave activity
Contractor:
Professor Esther Rodriguez-Villegas, Imperial College London
CRACK IT Challenge
The Trurat Show
Contractor:
Professor Douglas Armstrong, Actual Analytics Ltd
CRACK IT Challenge
Improving the predictive capacity of in vitro cytokine release assays to reduce animal use and drug attrition
Contractor:
Professor Martin Glennie, University of Southampton
CRACK IT Challenge
Improving biological integration of osseous and dermal tissues in macaque cranial implants
Principal Investigator:
Professor Alex Thiele
Institution:
Newcastle University
Strategic grant
NeuroScreen-3D: microfluidic microtiter plates for in vitro neurotoxicity screening
Contractor:
Dr Jos Joore, MIMETAS, BV
CRACK IT Challenge
Differentiating alveolar macrophage responses to inhaled medicines
Contractor:
Dr Ben Forbes, Kings College London
CRACK IT Challenge
A multiscale model to minimise animal usage in Leishmaniasis drug development
Contractor:
Professor Paul Kaye, University of York
CRACK IT Challenge
Development of high accuracy QSARs for mixtures to bridge the data gaps in skin and eye irritation
Contractor:
Dr Paul Thomas, KREATiS
CRACK IT Challenge
A new Drosophila-based strategy to study mitochondrial transport and neuronal ageing in vivo
Principal Investigator:
Dr Alessio Vagnoni
Institution:
King's College London
Fellowship
Developing an Organ on a Chip Model to Test the Therapeutic Efficacy of Adhirons in Breast Cancer
Principal Investigator:
Dr Darren Tomlinson
Institution:
University of Leeds
PhD Studentship
Development of functional 3D human intestinal mucosae to replace rodent models and improve the predictive accuracy of existing in vitro systems
Principal Investigator:
Professor Stefan Przyborski
Institution:
Durham University
PhD Studentship
Developing a Drosophila melanogaster model of the cardiac myocyte action potential to investigate function and performance
Principal Investigator:
Dr Jeremy Niven
Institution:
University of Sussex
PhD Studentship
Murinised Firefly Luciferase: A new direction towards immune-shielding and biological relevance
Principal Investigator:
Professor James Murray
Institution:
Cardiff University
PhD Studentship
Development of a novel cell based bitter taste assessment assay
Principal Investigator:
Dr Afzal Rahman Mohammed
Institution:
Aston University
PhD Studentship
Building brains in a dish - using ES cells to understand brain development
Principal Investigator:
Dr John Mason
Institution:
University of Edinburgh
PhD Studentship
Reducing animal usage in antifungal drug development: iRFP reporter strains and imaging infection
Principal Investigator:
Dr Donna MacCallum
Institution:
University of Aberdeen
PhD Studentship
Cas9 mediated in vitro gene editing in primary mammary epithelial cells
Principal Investigator:
Dr Walid Khaled
Institution:
University of Cambridge
PhD Studentship
Development and characterisation of a human ex vivo model of aneurysm
Principal Investigator:
Dr Jason Johnson
Institution:
University of Bristol
PhD Studentship
Reducing animal use in thrombosis research with an ex vivo injury model
Principal Investigator:
Dr Matthew Harper
Institution:
University of Cambridge
PhD Studentship
Developing Human Glioma OrganDot Cultures
Principal Investigator:
Professor William Gray
Institution:
Cardiff University
PhD Studentship
Refining an in vitro system of predictive biomarkers of in vivo liposome efficacy
Principal Investigator:
Dr Andrew Devitt
Institution:
Aston University
PhD Studentship
Refinement of hematopoietic cell transplantation using optical imaging in zebrafish
Principal Investigator:
Professor Margaret Dallman
Institution:
Imperial College London
PhD Studentship
Microfluidic networks: an in vitro 3D culture system for the investigation of neuron-glial interactions in neurodegeneration
Principal Investigator:
Dr Tomas Bellamy
Institution:
University of Nottingham
PhD Studentship
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