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Transfer of a non-human primate (NHP) in vitro functional assay for the early evaluation of TB vaccine candidates and the associated immune response

Institution: 

  • University of Oxford
  • Skills and Knowledge Transfer grant

High-throughput in vitro culture system for Cryptosporidium oocysts: replacing animals in research

Institution: 

  • Cardiff University
  • Skills and Knowledge Transfer grant

The use of PrP transgenic Drosophila to replace and reduce mice in the bioassay of mammalian prions

Institution: 

  • University of Cambridge
  • Skills and Knowledge Transfer grant

Dissemination of refinements in mouse experimental stroke models to the scientific community

Institution: 

  • University of Leicester
  • Skills and Knowledge Transfer grant

Using chicken eggs to advance the 3Rs in cancer drug discovery

  • CRACK IT Solution

Design, Fabrication and Testing of a Mouse Embryo Culture Chip

  • CRACK IT Challenge

Chair restraint training of non-human primates

  • Office-led project

Integrated web platform for agro-chemical formulation toxicity classification and data sharing

  • CRACK IT Challenge

Neuroinflammation and nociception in a dish

  • CRACK IT Solution

Rodent models of stroke

  • Office-led project

Opportunities to apply the 3Rs in the safety assessment of nanomaterials

  • Office-led project

Maximising the success of bile duct cannulation studies

  • Office-led project

Development of new experimental models to understand the genetic basis of allergic bronchopulmonary aspergillosis

Institution: 

  • University of Manchester
  • Fellowship

An industrial standard cancer drug development platform using human induced pluripotent stem cell technology

Institution: 

  • Newcastle University
  • Fellowship

Intestinal organoids as a replacement strategy to unravel early host intestinal epithelia interactions with whipworms

Institution: 

  • Wellcome Trust Sanger Institute
  • Fellowship

Interrogating the mouse visual system by automated analysis of voluntary behaviour

Institution: 

  • University of Manchester
  • Fellowship

The establishment of left-right asymmetry in mammalian development

Institution: 

  • University of Liverpool
  • Fellowship

Application of a 3D hydrogel-based model to replace use of animals for passaging patient-derived xenografts

Institution: 

  • University of Nottingham
  • PhD Studentship

Investigation of key inflammatory cells & mediators in zebrafish larval tailfin & heart repair/regeneration following resolution of inflammation

Institution: 

  • University of Edinburgh
  • PhD Studentship

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