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Embryonic zebrafish models of HACD1-deficiency to replace mammals in congenital myopathy and lipidomic research

Institution: 

  • University of Liverpool
  • PhD Studentship

Exploring the role of matrix encapsulation on early developmental decisions using non-animal sourced hydrogels

Institution: 

  • University of Nottingham
  • PhD Studentship

Ensuring humane deaths for laboratory birds

Institution: 

  • University of Edinburgh
  • PhD Studentship

High fidelity computational approaches to exploit new structures of cardiac ion channels

Institution: 

  • University of Manchester
  • PhD Studentship

Refinement of pre-exposure programs to reduce the use of fish in proliferative kidney disease monitoring in aquaculture

Institution: 

  • University of Nottingham
  • PhD Studentship

Modulating Macrophage Phenotypes During Infection In Zebrafish

Institution: 

  • University of Sheffield
  • PhD Studentship

3D patient-derived organoids: A viable and complementary model to study neural system dysfunction in Alzheimer's Disease

Institution: 

  • University College London
  • PhD Studentship

Efficacy of artificial imprinted antibodies in driving unwarranted immune responses

Institution: 

  • Newcastle University
  • PhD Studentship

Human stem cell models of de novo tumorigenesis to replace the use of animals for the study of cancer initiation

Institution: 

  • University of Nottingham
  • PhD Studentship

Revision of the guidelines on animal use and welfare in cancer research

  • Office-led project

Development of a New Human Model of Lung Squamous Cell Carcinoma Progression

Institution: 

  • University of Manchester
  • Project grant

Validation of an in vitro humanised 3D haematopoietic system to investigate haematological malignancies.

Institution: 

  • University of Glasgow
  • Project grant

Refinement of tickling protocols to improve positive animal welfare in laboratory rats

Institution: 

  • Scotland’s Rural College
  • Project grant

Defining drug delivery into and across the oral mucosa using a tissue engineering and mathematical modelling approach

Institution: 

  • University of Sheffield
  • Project grant

Reducing and replacing the animal cost of functional genetics in African trypanosomiasis

Institution: 

  • University of Nottingham
  • Project grant

Live monitoring of foreign-body response in animals by diffuse Raman spectroscopy

Institution: 

  • University of Nottingham
  • Project grant

Establishing Drosophila melanogaster as part of the pre-clinical pipeline for anti-metastatic cancer drug discovery

Institution: 

  • University of Sheffield
  • Project grant

Go North: Expanding the use of the chick embryo model in cancer research to a multiuser facility at the University of Strathclyde.

Institution: 

  • University of Liverpool
  • Skills and Knowledge Transfer grant

Acquisition of the Drosophila model system to understand mechanisms of innate immunity regulation by chromatin dynamics

Institution: 

  • University of Essex
  • Skills and Knowledge Transfer grant

Determining the efficacy and safety of cancer chemotherapeutics for cholangiocarcinoma (CCA) using Human Precision Cut Tissue Slices (hPCTS).

Institution: 

  • Liverpool John Moores University
  • Skills and Knowledge Transfer grant

Establishing the novel ex-vivo focal demyelination model of Multiple Sclerosis in other laboratories to reduce and replace live animal use.

Institution: 

  • Cardiff University
  • Skills and Knowledge Transfer grant

Adoption of a mouse model of veterinary filariasis for preclinical drug testing

Institution: 

  • Liverpool School of Tropical Medicine
  • Skills and Knowledge Transfer grant

A non-protected larval zebrafish model for the investigation of novel strategies to protect against nerve agent-induced toxicity and seizures

Institution: 

  • University of Portsmouth
  • Skills and Knowledge Transfer grant

Cerebral organoid models for optical investigation of neural circuit dynamics in neurodegenerative diseases

Institution: 

  • Imperial College London
  • Skills and Knowledge Transfer grant

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