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Displaying 1 - 25 of 297
Review of animal use requirements in WHO biologics guidelines
Office-led project
Preneoplastic Pancreatic (PanIN) Organoids as an in vitro Model of Pancreatic Cancer Progression
Project grant
University of Liverpool
In vitro, off-host, rearing of the poultry red mite to supply parasites for development of new control methods
Project grant
Moredun Research Institute
Using ex vivo organotypic cultures to investigate donor cell integration in the gut
Project grant
University College London
A Drosophila single-cell resource for brain metabolism research
Project grant
The Francis Crick Institute
Development of a Drosophila-based platform to replace and reduce animal experimentation in epilepsy research
Project grant
King's College London
Developing stem cell-derived macrophages to study host pathogen interactions and advance strategies to combat globally important disease in the pig
Project grant
University of Edinburgh
Establishment of novel macrophage cell lines to study the pathogenesis of respiratory bacterial pathogens in lung alveolar macrophages
Skills and Knowledge Transfer grant
University of Plymouth
MacuSIM: A microfluidic, in vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials
Fellowship
University of Southampton
A novel embryonic zebrafish model to replace mammals in the study of 3-hydroxyacyl CoA dehydratase 1-associated muscle disorders
Fellowship
University of Liverpool
A computational framework to investigate the mechanical role of the extracellular matrix in tissue development and disease
Fellowship
University College London
Development of non-mammalian, preclinical screening tools for the predictive analysis of cardiotoxicity
PhD Studentship
University of East Anglia
Use of induced pluripotent stem cell derived cardiomyocytes to test the consequences of genetic variants in atrial and ventricular arrhythmias
PhD Studentship
University of Birmingham
INDUCE-seq: a novel tool for next generation risk assessment
PhD Studentship
Cardiff University
Developing an in silico, spectroscopic imaging toolkit for assessing skin penetration
PhD Studentship
University of Surrey
An improved C. elegans model of Alzheimer's disease to monitor neuronal signalling activity
PhD Studentship
University of Leeds
Modelling O-GlcNAc transferase intellectual disability syndrome in Drosophila
PhD Studentship
University of Dundee
A 3Rs approach to assess drug toxicity on the mammalian embryo during early pregnancy in vitro
PhD Studentship
University of Liverpool
Direct replacement of secondary antibodies by Affimer proteins
PhD Studentship
University of Leeds
3D bio-printing human pluripotent stem cell-derived skeletal muscle constructs for disease modelling and drug discovery
PhD Studentship
Queen Mary University of London
Ex vivo drug screening using human tissue to personalise cancer therapy and replace murine avatars
PhD Studentship
University of Sheffield
A novel tool that embeds 3Rs principles in multiple sclerosis research
PhD Studentship
University of Glasgow
A living biobank of post-surgical residual glioblastoma to replace animal studies
PhD Studentship
University of Sheffield
Development of an in vitro model to dissect the mechanism of fungal persistence in the cystic fibrosis lung
PhD Studentship
University of Manchester
Validating CRISPR-engineered human pluripotent stem cell-derived cardiomyocytes as tools to assist with toxicity profiling, adverse drug reaction notices and black box warnings
Technologies to Tools grant
University of Nottingham

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