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CRACK IT
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Supporting the adoption of microphysiological systems for COVID research
Current contact:
Dr Anthony Holmes
Office-led project
Breeding and colony management
Current contact:
Dr Esther Pearl
Office-led project
Review of animal use requirements in WHO biologics guidelines
Current contact:
Dr Anthony Holmes
Office-led project
Rodent high-yield behavioural experiments
Current contact:
Dr Chris Barkus
Office-led project
Application of non-animal approaches for decision-making in chemical safety assessment
Current contact:
Dr Fiona Sewell
Office-led project
Revision of the ARRIVE guidelines
Current contact:
Dr Nathalie Percie du Sert
Office-led project
Human Tissue for Safety Pharmacology
Current contact:
Dr Anthony Holmes
Office-led project
Improving the predictive power of models for cancer research
Current contact:
Dr Anthony Holmes
Office-led project
Chair restraint training of non-human primates
Current contact:
Dr Mark Prescott
Office-led project
Rodent models of stroke
Current contact:
Dr Nathalie Percie du Sert
Office-led project
Applying exposure science to increase the utility of non-animal data in efficacy and safety testing
Current contact:
Dr Natalie Burden
Office-led project
Opportunities to apply the 3Rs in the safety assessment of nanomaterials
Current contact:
Dr Natalie Burden
Office-led project
Maximising the success of bile duct cannulation studies
Current contact:
Dr Natalie Burden
Office-led project
Review of the use of two species in regulatory toxicology studies
Current contact:
Dr Helen Prior
Office-led project
Assessing the predictive value of safety pharmacology studies
Current contact:
Dr Helen Prior
Office-led project
Refinement of rodent and non-rodent housing during telemetry recordings
Current contact:
Dr Helen Prior
Office-led project
Review of global data requirements for plant protection products
Current contact:
Dr Natalie Burden
Office-led project
Reducing repetition of regulatory vertebrate ecotoxicology studies
Current contact:
Dr Natalie Burden
Office-led project
Utilising QSARs to predict fish acute toxicity of pesticide metabolites
Current contact:
Dr Natalie Burden
Office-led project
Applying the one concentration approach in fish bioaccumulation studies
Current contact:
Dr Natalie Burden
Office-led project
Applying the threshold approach in fish acute toxicity studies
Current contact:
Dr Natalie Burden
Office-led project
Assessing the need for chronic fish studies on formulated pesticides
Current contact:
Dr Natalie Burden
Office-led project
Advancing the development and application of non-animal technologies (NATs)
Current contact:
Dr Anthony Holmes
Office-led project
Applying mathematics to 3Rs problems
Current contact:
Dr Anthony Holmes
Office-led project
Use of microsampling to reduce and refine animal use
Current contact:
Dr Helen Prior
Office-led project
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