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Generation of functionally mature pancreatic organoids as a replacement strategy for animal-models of pancreatitis and pancreatic cancer

Institution: 

  • King's College London
  • Fellowship

Understanding brain regeneration in a zebrafish larval model of intracerebral haemorrhage

Institution: 

  • University of Manchester
  • Fellowship

Optimisation and validation of 3D models of progressive human lung fibrosis

Principal Investigator: 

  • Mr Joseph Bell

Institution: 

  • University of Southampton
  • Fellowship

Supporting the adoption of microphysiological systems for COVID research

  • Office-led project

Replacement of animal use in measuring cardiomyocyte response to drug safety profiling using a novel NMR metabolomics technology

Institution: 

  • University of Liverpool
  • PhD Studentship

Investigating biomechanical responses in healthy and diseases ageing cartilage - a tissue engineering approach

Institution: 

  • Newcastle University
  • PhD Studentship

Targeted protein degradation as a novel approach to study protein function in human platelets

Institution: 

  • University of Bristol
  • PhD Studentship

A novel in vitro reporter system for blood stem cell activity

Institution: 

  • University of York
  • PhD Studentship

Understanding how altered brain metabolism causes mitochondrial disease

Institution: 

  • King's College London
  • PhD Studentship

Combining a fully synthetic hydrogel with human intestinal organoids to model pathological matrix remodelling in Inflammatory Bowel Disease

Institution: 

  • King's College London
  • PhD Studentship

A novel Drosophila model of chronic inflammatory lung disease to explore airway damage, inflammation and infection in vivo

Institution: 

  • University of Bristol
  • PhD Studentship

3D bioprinted microtissues to develop patient-specific non-animal technologies (NAT) in cancer drug development

Institution: 

  • Northumbria University
  • PhD Studentship

Insects as models to study wound healing, infection and the wound microbiome

Institution: 

  • Brunel University
  • PhD Studentship

A 3Rs approach to investigate the feto-maternal interface: visualisation of pathogen and antibody in a 3D in vitro human placental model

Institution: 

  • University of Liverpool
  • PhD Studentship

Development and validation of 3D in vitro dormant myeloma cell models to reduce and replace animal studies

Institution: 

  • University of Sheffield
  • PhD Studentship

Drug risk assessment and repurposing using biomimetic chromatography and body-on-chip technology

Institution: 

  • University of Edinburgh
  • PhD Studentship

Review of animal use requirements in WHO biologics guidelines

  • Office-led project

Preneoplastic Pancreatic (PanIN) Organoids as an in vitro Model of Pancreatic Cancer Progression

Institution: 

  • University of Liverpool
  • Project grant

In vitro, off-host, rearing of the poultry red mite to supply parasites for development of new control methods

Institution: 

  • Moredun Research Institute
  • Project grant

Using ex vivo organotypic cultures to investigate donor cell integration in the gut

Institution: 

  • University College London
  • Project grant

A Drosophila single-cell resource for brain metabolism research

Institution: 

  • The Francis Crick Institute
  • Project grant

Development of a Drosophila-based platform to replace and reduce animal experimentation in epilepsy research

Institution: 

  • King's College London
  • Project grant

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