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Ex vivo drug screening using human tissue to personalise cancer therapy and replace murine avatars

Institution: 

  • University of Sheffield
  • PhD Studentship

A novel tool that embeds 3Rs principles in multiple sclerosis research

Institution: 

  • University of Glasgow
  • PhD Studentship

A living biobank of post-surgical residual glioblastoma to replace animal studies

Institution: 

  • University of Sheffield
  • PhD Studentship

Development of an in vitro model to dissect the mechanism of fungal persistence in the cystic fibrosis lung

Institution: 

  • University of Manchester
  • PhD Studentship

Translating microvascularised chips of a nephrotoxicity model

Institution: 

  • Queen Mary University of London
  • Technologies to Tools grant

Developing a rapid method for identification of key proteins that define tissues to create an array of tissue-specific hydrogels for human-relevant in vitro 3D culture

Institution: 

  • University of Nottingham
  • Technologies to Tools grant

Platform to phenotype liver metabolic disorders

Principal Investigator: 

  • Professor Ludovic Vallier

Institution: 

  • University of Cambridge
  • Technologies to Tools grant

Developing a chick embryo model to aid in development of personalised therapies for malignant pleural mesothelioma

Institution: 

  • University of Liverpool
  • Project grant

Engineering Galleria Mellonella as a model for infection, immunity and inflammation

Institution: 

  • University of Exeter
  • Project grant

Galleria mellonella as an infection model for viral pathogens

Institution: 

  • University of Exeter
  • Project grant

A novel Drosophila platform to replace the use of mice and zebrafish for the study of ER-mitochondria interactions

Institution: 

  • King's College London
  • Skills and Knowledge Transfer grant

Fully humanised 3D vascular perfused model for breast cancer modelling and therapeutic screening

Institution: 

  • University of Aberdeen
  • Skills and Knowledge Transfer grant

Replacing the need for patient-derived xenografts and matrigel organoid culture as preclinical models for breast cancer

Institution: 

  • The University of Manchester
  • Skills and Knowledge Transfer grant

Assessing the relevance of Galleria mellonella to antibiotic drug discovery for pulmonary infections

Institution: 

  • King's College London
  • Skills and Knowledge Transfer grant

Transfer of the epicardial-cardiac organotypic culture model to support the ex vivo screening of gene therapy candidates

Institution: 

  • University of Surrey
  • Skills and Knowledge Transfer grant

DARTpaths: Mapping developmental and reproductive toxicity (DART) genes and pathways for cross-species comparison of toxic compound effects

  • CRACK IT Challenge

Focused molecular understanding of hypertrophic cardiomyopathy using CRISPR-engineered human pluripotent stem cell-derived cardiomyocytes

Institution: 

  • University of Nottingham
  • Fellowship

From ageing to space travel: Developing an organotypic model of skeletal tissue disuse for understanding degeneration in altered environments

Institution: 

  • University of Birmingham
  • Fellowship

Refining the lung cancer mouse model through environmental enrichment

Institution: 

  • The Francis Crick Institute
  • Fellowship

Development of an invertebrate model of alternating hemiplegia of childhood

Institution: 

  • University of Leeds
  • PhD Studentship

Experimental evolution of Pseudomonas aeruginosa in media replicating the conditions of the upper and lower airways

Institution: 

  • University of Liverpool
  • PhD Studentship

Development and characterization of a novel endothelialized in vitro model of human atherothrombosis

Institution: 

  • Manchester Metropolitan University
  • PhD Studentship

An organotypic model of the bone remodelling process

Institution: 

  • University of Birmingham
  • PhD Studentship

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