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Displaying 1 - 23 of 23
Development of an AOP for cardiotoxicity mediated by the blockade of L-type calcium channel
Strategic grant
Brunel University
Improving biological integration of osseous and dermal tissues in macaque cranial implants
Strategic grant
Newcastle University
DictyMyc: Using Dictyostelium to study the genetic basis of Mycobacterium bovis intracellular infection
Strategic grant
University of Surrey
Developing and validating an in vitro mycobacterial challenge model to facilitate TB vaccine research and minimise in vivo challenge
Strategic grant
University of Oxford
A bovine alveolus model to replace cattle in the study of host-pathogen interactions in bovine tuberculosis
Strategic grant
University of Surrey
A non-mammalian model to study innate immune modulation of airways remodelling in asthma
Strategic grant
University of Sheffield
Developing a non-animal model system to investigate bitter tastants as new treatments for asthma
Strategic grant
Royal Holloway University of London
Developing a model for the study of respiratory inflammation in the zebrafish
Strategic grant
Imperial College London
Use of Drosophila models to explore the function of asthma susceptibility genes
Strategic grant
University of Southampton
Ultrasound mediated bioluminescence tomography for high sensitivity, high spatial resolution 3D imaging
Strategic grant
University of Nottingham
Targeted, radiolabelled near-infrared quantum dots for high sensitivity and resolution, dual modality imaging of human tumours in mice
Strategic grant
University of Nottingham
Non-invasive real-time bioluminescence imaging in living mice to interrogate transcription factor activity and fate of engrafted stem cells
Strategic grant
Manchester Metropolitan University
Labelled IMS TAG Proteins for Quantitative Mass Spectrometry Imaging
Strategic grant
Sheffield Hallam University
Implanted optical imaging laboratories for deep-tissue in vivo imaging
Strategic grant
University of Glasgow
Developing an integrated "in vitro carcinogenicity predictive tool" utilising in vitro cell signalling and cell behaviour assessment coupled with in vitro genotoxicity data
Strategic grant
Swansea University
Assessing the humaneness of gas euthanasia techniques for laboratory rodents
Strategic grant
Newcastle University
A tissue engineered construct to monitor mucosal immunity in asthma
Strategic grant
University of Southampton
Developing a platform of in vitro models of asthmatic and healthy lung: an alternative to the use of animals in asthma research
Strategic grant
University of Nottingham
Imprecision and importance: Probabilistic graphical models in toxicology
Strategic grant
University of York
Structural identifiability and indistinguishability analysis as tools for quantitative and systems pharmacology to support the 3Rs
Strategic grant
University of Warwick
Uncertainty and confidence in applying mathematical models and in vitro data in toxicological safety assessments
Strategic grant
University of Leeds
Prediction of human cardiotoxic QT prolongation using in vitro multiple ion channel data and mathematical models of cardiac myocytes
Strategic grant
University of Oxford
Development of human epithelial cell transformation models for carcinogen screening, employing defined phenotypic endpoints mechanistically representative of rate-limiting events in human carcinogenesis
Strategic grant
Brunel University