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DARTpaths: Mapping developmental and reproductive toxicity (DART) genes and pathways for cross-species comparison of toxic compound effects
CRACK IT Challenge
Shell
Mouse Smart Hoppers (Moshers)
CRACK IT Challenge
MRC Harwell Institute
Validating CombiDART in the agrochemical sector
CRACK IT Solution
Syngenta
Development and evaluation of the Animal Welfare Assessment Grid (AWAG)
CRACK IT Solution
Veterinary Health Innovation Engine (vHIVE)
RespiraTox: In silico model for predicting human respiratory irritation
CRACK IT Challenge
University of Birmingham
Shell
A new sensor platform combining plastic antibodies with simple thermal detection
CRACK IT Solution
MIP Diagnostics Limited
Validating the cross-species comparative in silico platform (CRISP)
CRACK IT Solution
Dow AgroSciences
3D hiPSC derived laminated retinal model as a tool for toxicology studies
CRACK IT Challenge
Newcastle University
Merck
Microfluidic Automated Platform for Osteoarthritis Drug Screening (MA-PODS)
CRACK IT Challenge
Newcastle University
GSK
Using chicken eggs to advance the 3Rs in cancer drug discovery
CRACK IT Solution
Design, Fabrication and Testing of a Mouse Embryo Culture Chip
CRACK IT Challenge
MRC Harwell
Integrated web platform for agro-chemical formulation toxicity classification and data sharing
CRACK IT Challenge
University of York
Dow AgroSciences and Syngenta
Neuroinflammation and nociception in a dish
CRACK IT Solution
Non-invasive in vivo tissue imaging with functional optical coherence tomography (OCT)
CRACK IT Solution
University of Washington
TruLarv Galleria mellonella - a model host for infection studies, toxicity testing and drug development (Partnering with Demuris)
CRACK IT Solution
Demuris
TruLarv Galleria mellonella - a model host for infection studies, toxicity testing and drug development (Partnering with Envigo)
CRACK IT Solution
Envigo
Developing an ethical, sustainable, human sensory neuron culture model for use in therapeutic pain research
CRACK IT Challenge
University of Glasgow
Grünenthal
3D hiPSC derived skin model and in-silico skin modelling of metabolism
CRACK IT Challenge
Newcastle University
GlaxoSmithKline
A human IPS cell model for gene therapy vector safety evaluation
CRACK IT Challenge
Brunel University
GlaxoSmithKline
A Brave New Homecage
CRACK IT Challenge
Strathclyde University
MRC Harwell
Rodent Big Brother
CRACK IT Solution
Queen Mary
Portable bioluminescence test for botulinum neurotoxin
CRACK IT Solution
Affimers: animal free alternatives to antibodies
CRACK IT Solution
Mary Lion Centre at MRC Harwell
Comprehensive target screening by label-free cell microarray profiling to reduce animal efficacy and toxicology studies in drug discovery
CRACK IT Solution
Retrogenix
A novel product for reducing animal numbers in the production of transgenic mice
CRACK IT Solution
Cancer Research K Transgenic Service

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