Welfare assessment e-learning resource launched
A resource to help researchers and animal care staff to identify signs of good and poor welfare.
Grimace Scale posters
Posters on the use of facial expressions to assess pain in laboratory animals, now including rabbits.
ARRIVE guidelines at five
New blog post explores the surge of support for the guidelines, which now has over 600 endorsements from international journals.
New article in our series on genetically altered mice
It starts at the very beginning: the importance of neonate assessment
Working collaboratively to overcome bovine tuberculosis
A blog on how we are tackling bovine tuberculosis (bTB) using the 3Rs.
Human cell and regenerative medicine technologies report
A report of the April 2015 workshop co-hosted by the NC3Rs has been published.
Call for CRACK IT Challenges
Do you have an idea for our next CRACK IT Challenge? We are now inviting submissions from potential Sponsors.
Order the ARRIVE guidelines
Improve the reporting of research using animals by maximising information published and minimising unnecessary studies.
Experimental Design Assistant
Our online tool for in vivo researchers to improve their experimental design.

Pioneering Better Science


The NC3Rs is the UK's national organisation which leads the discovery and application of new technologies and approaches to replace, reduce and refine the use of animals for scientific purposes (the 3Rs).

We collaborate with scientists and organisations from across the life sciences sector, nationally and internationally, including universities, the pharmaceutical, chemical and consumer products industries, other research funders, and regulatory authorities.

We fund 3Rs research, training and career development, support open innovation and commercialisation of 3Rs technologies, and stimulate changes in policy, regulations and practice relating to the use of animals.

Keep in touch

Our open innovation programme supports the development of marketable products and improved business processes with 3Rs benefits.



Setting out the NC3Rs vision for the next ten years, the publication is divided into five inter-related areas; Practice, Procedures, People, Places and Policy. 

Click here to read our ten year vision, from 2015-2025.

Latest news

Invertebrates such as Drosophila melanogaster (...
A collaborative research team looked at improving...
A new e-learning resource focusing on the...

Current funding

Submission date:
Deadline for invited full applications via Je-S.

Submission date:
We are now inviting submissions from Sponsors for Challenges.

A Special Interest Group to connect technology developers with the business community in the development of non-animal technologies (NATs) for improved efficacy and safety testing.


From the blog

Bovine tuberculosis (bTB) is one of the biggest...
The ARRIVE guidelines were launched in 2010, and...
Dr Daniel Adams (pictured below), University of...





SEARCHBreast was established under an NC3Rs...




The 11th edition of the biennial Conference and...