2016 CRACK IT Challenges announced
£2.8 million available for four new Challenges: applications sought from SME and academic consortia.
Using personalised organoids to reduce animal testing
A blog on Hayley Francies' research, highly commended in our 3Rs Prize competition.
Explore the science we fund
Our programmes are divided into research funded through grants & early career awards, CRACK IT & office led research.
NC3Rs/ABPI collaboration
New project will focus on the use of the second species in regulatory toxicology studies.
Head masks adapted to refine primate research
Personalised masks, originally developed for cancer patients, adapted for macaques.
Resources from the NC3Rs
We provide an extensive library of 3Rs resources including guidelines, practical information and themed hubs.
NC3Rs/IAT Animal Technicians’ Symposium 2016
Register now for this free event. Travel bursaries available, apply by 30 August 2016. Attendance carries 5 IAT CPD points.
Using computational models to replace toxicity testing
QSAR models could be used to predict fish acute toxicity of pesticide metabolites.
Translation of safety pharmacology models
Assessing the predictivity of rodent models of CNS safety pharmacology.
2016 Primate Welfare Meeting
A key event for researchers, veterinarians, technologists and others involved with the care and use of non-human primates.
What are the 3Rs?
The principles of the 3Rs (Replacement, Reduction and Refinement) were developed as a framework for humane animal research.
Expert opinion pieces on genetically altered mice
A series from Dr Sara Wells, Director of the Mary Lyon Centre, MRC Harwell Institute.

Pioneering Better Science


The NC3Rs is the UK's national organisation which leads the discovery and application of new technologies and approaches to replace, reduce and refine the use of animals for scientific purposes (the 3Rs).

We collaborate with scientists and organisations from across the life sciences sector, nationally and internationally, including universities, the pharmaceutical, chemical and consumer products industries, other research funders, and regulatory authorities.

We fund 3Rs research, training and career development, support open innovation and commercialisation of 3Rs technologies, and stimulate changes in policy, regulations and practice relating to the use of animals.

Keep in touch

Our open innovation programme supports the development of marketable products and improved business processes with 3Rs benefits.



Current funding

Submission date:
The 2016 CRACK IT Challenges will launch at a meeting on Thursday 8 September

Submission date:
We are inviting applications, via Je-S, to our new career development scheme.