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International 3Rs Prize now open for applications. £30k prize (£2k personal award) for outstanding science with demonstrable 3Rs impacts.

NC3Rs | 20 Years: Pioneering Better Science

Dr Esther Pearl

Position
Programme Manager – Experimental Design
Portrait of Dr Esther Pearl

Esther supports our work in experimental design, analysis and reporting. She works on the implementation of the ARRIVE guidelines and the Experimental Design Assistant (EDA). She is a member of the Policy and Outreach Group.

NC3Rs publications

Karp NA, Pearl EJ, Stringer EJ, Barkus C, Ulrichsen JC, Percie du Sert N (2022). A qualitative study of the barriers to using blinding in in vivo experiments and suggestions for improvement. PLoS Biol. doi: 10.1371/journal.pbio.3001873 

Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M,  Garner P, Holgate ST, Howells DH, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H (2020). The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research. PLoS Biol 18(7): e3000410. doi: 10.1371/journal.pbio.3000410

The ARRIVE guidelines 2.0 are also published in BMC Vet Res, BMJ Open Science, Br J Pharmacol, J Exp Physiol, J Cerebr Blood F Met, J Physiol and Vet Clin Pathol.

Percie du Sert N, Ahluwalia A, Alam S, Avey MT, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M,  Garner P, Holgate ST, Howells DH, Hurst V, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H (2020). Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2.0. PLoS Biol 18(7): e3000411. doi: 10.1371/journal.pbio.3000411

Percie du Sert N, Ahluwalia A, Alam S, Avey MT, Baker M, Browne W, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lidster K, Maccallum CJ, Macleod M, Pearl EJ, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2019). Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019. bioRxiv 703355. doi: 10.1101/703355

Qualifications

PhD, Biochemistry 
University of Otago, 2003 – 2006 
Requirements for splicing by Cne PRP8, a novel intein from Cryptococcus neoformans

BSc (Hons), Biochemistry 
University of Otago, 1999 – 2003