3Rs resources

The NC3Rs and the 3Rs during COVID-19
Advice and resources for researchers and animal care staff.
Breeding and colony management
Guidance on re-establishing colonies following COVID-19 lockdown or any other interruption.
Non-human primate welfare
A resource hub focused on opportunities to refine the use of non-human primates.
Webinars
Register for our upcoming webinars and watch recordings of past presentations on a wide range of 3Rs topics.
Embedding the 3Rs in your return to research plans
Key considerations and resources for researchers working with laboratory animals.
3Rs advice for project licence applicants
Guidance on addressing the 3Rs aspects of a Home Office project licence application.
Experimental design
Resources to help you improve the design and reporting of your in vivo research.
Toxicology and regulatory sciences resources
Read or subscribe to our e-newsletter Tox News and download our bibliography.
E-learning resources
Online modules funded by the NC3Rs, which are freely available for training and continuing professional development.
Animal technician hub
Resources to help laboratory animal technicians implement the 3Rs, including our quarterly Tech3Rs newsletter.
Videos: non-aversive mouse handling in practice
Hear from animal care staff championing non-aversive mouse handling in their facilities.
Rat tickling
Resources on this positive handling technique, provided by the Gaskill Lab at Purdue University.
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3Rs resources

We provide an extensive library of 3Rs resources. This includes guidelines, practical information and themed hubs. Links to publications, other online resources, and video and training materials are also provided.

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Hubs and microsites

Advice and resources for researchers and animal care staff.
Upcoming webinars and recordings of past webinars on different 3Rs topics.
Guidance on key considerations and resources for researchers returning to working with laboratory animals.
Demonstrating the 3Rs in principle and practice.
Guidance and resources to help applicants address the 3Rs aspects of a Home Office project licence application.
Resources and information on the 3Rs aimed at a non-specialist audience.
NC3Rs programmes in drug and chemical safety testing.
Resources to help laboratory animal technicians implement the 3Rs.
Refining blood sampling from laboratory animals - advice on technique, route and volumes.
Guidance on re-establishing colonies after a pause (e.g. COVID-19 lockdown) with an emphasis on minimising the number of mice used.
Online modules funded by the NC3Rs, which are freely available for training and continuing professional development.
Resources to aid researchers improve the design and reporting of research using animals.
Information to help with the implementation of approaches to reduce and refine the use of GA mice.
Posters and other resources on the use of grimace scales to assess pain in laboratory animals.
Refining the housing and husbandry of common laboratory animal species.
Non-aversive methods for handling mice.
Resources to help researchers access and use human tissue.
A dedicated, open access portal for our Grant holders to showcase their 3Rs research.
How we support funders to embed the 3Rs in their policies and practice.
A dedicated website of online tutorials and guidance to support the adoption of best practice for commonly used procedures in animal research.
Resources on rat tickling and how it can be used to promote positive human-animal interactions, provided by the Gaskill Lab at Purdue University.
Learn more about why the single-use of needles should be standard practice and how to implement this in your facility.
Resources and outputs from our programmes related to laboratory rodent welfare.
Opportunities to refine the use of non-human primates.