Webinar: The NC3Rs 3Rs Prize Award Announcement
Register for a virtual announcement of the annual 3Rs Prize Award on Wednesday 10 June at 4pm (BST).
The NC3Rs and the 3Rs during COVID-19
An update on what we are doing to support the research community.
3Rs for the public
Learn more about the 3Rs and their importance in research.
Discover publications from NC3Rs researchers
Visit our open access publication portal, hosted by F1000Research.
Advancing cardiovascular science with 3Rs methods
We highlight the scientific and 3Rs impacts of two NC3Rs/BHF-funded PhD Studentships.
Burrow into our citizen science project
Contribute to lab mouse welfare via this project, a collaboration with MRC Harwell.
Rat tickling for improved welfare
Resources from the Gaskill Lab at Purdue University to support you in putting this positive handling technique into practice.
Explore the NC3Rs Innovation Platform
Learn more about our CRACK IT programme and how you can get involved.
Experimental design
Resources to help you improve the design and reporting of your in vivo research.
Minimising aggression in group-housed male mice
Read the results of our international mouse aggression study, recently published in Scientific Reports.
Tech3Rs: our animal technician newsletter
Sign up to receive free copies for UK facilities and stay up to date with the 3Rs.
Explore the evidence base for refined mouse handling
Our new printable table summarises the research published to date.

The NC3Rs: Pioneering better science


We help the research community use the latest science and technology to replace animal studies, providing new approaches for biomedical research and avoiding the time and cost associated with in vivo models. Where the use of animals is still required, we support researchers to design the best experiments so that their methods and findings are robust and reproducible. We provide information and guidance on the latest knowledge to improve laboratory animal welfare.

Keep in touch

Latest news

Approaches to evaluating environmental enrichment

How technicians across the UK introduce new environmental enrichment into their facilities and what barriers they face.

Pair housing of dogs in metabolism studies

Covance and Novo Nordisk collaborated to investigate whether dogs could be pair-housed during pharmaceutical metabolism studies.

E-learning and the 3Rs

How e-learning can complement more traditional approaches when training those working with laboratory animals.

Using an award scheme to promote 3Rs innovation

How AstraZeneca’s 3Rs award scheme supports communication and innovation in the 3Rs across its global sites.

International survey on non-aversive handling of laboratory mice

A new paper presents the results of the survey, exploring the prevalence of non-aversive handling methods and obstacles to uptake.