10 years of CRACKing IT
Read about our programme of events celebrating our open innovation programme's first ten years.
Vacancies at the NC3Rs
Learn more about current opportunities to join the NC3Rs team.
Listen to "3 Minute 3Rs"
A monthly podcast highlighting the latest 3Rs research, presented by Lab Animal, the North American 3Rs Collaborative and the NC3Rs.
2021 PhD Studentship scheme now open for applications
Prospective supervisors should submit informal outlines for this year's scheme by Wednesday 12 May.
Research culture and the 3Rs
Resources to help you strengthen the research culture of your group or institution through applying the 3Rs effectively.
Visit the NC3Rs gateway
Read detailed 3Rs method articles from our grant holders via our open access portal.
NC3Rs webinars
Register for our upcoming webinars and watch recordings of past presentations on a wide range of 3Rs topics.
3Rs for the public
Learn more about the 3Rs and their importance in research.
The NC3Rs and the 3Rs during COVID-19
An update on what we are doing to support the research community.
Download the latest Tech3Rs
Our quarterly newsletter for animal technicians can help you discover new ways to put the 3Rs into practice in your facility.
Zebrafish welfare
Opportunities to refine the use of laboratory zebrafish, including common procedures.
Animal technician resources
A range of resources to help animal care staff implement the 3Rs.

The NC3Rs: Pioneering better science


We help the research community use the latest science and technology to replace animal studies, providing new approaches for biomedical research and avoiding the time and cost associated with in vivo models. Where the use of animals is still required, we support researchers to design the best experiments so that their methods and findings are robust and reproducible. We provide information and guidance on the latest knowledge to improve laboratory animal welfare.


Find out more: About the 3Rs | About the NC3Rs

Keep in touch

Latest news

Refining non-human primate vaccine studies in the age of COVID-19

A new review paper co-authored by NC3Rs staff sets out opportunities to refine vaccine studies that use non-human primates.

Meet our new Training Fellows

Four new awards will support early career researchers to prepare for an independent career in their chosen 3Rs field.

10 years of CRACKing IT

Celebrating 10 years of our challenge-led, milestone-driven funding competition, CRACK IT Challenges.

New NC3Rs Board members appointed

The five new members bring expertise in animal welfare, neurobiology, glycobiology, systems biology and in vitro toxicology.

ARRIVE guidelines 2.0 now available in six languages

The guidelines are now available in French, German, Chinese, Dutch, Portuguese and Italian.