New platform to maximise the 3Rs impact of NC3Rs-funded research
The NC3Rs Gateway is an open access publication portal dedicated to 3Rs approaches, hosted by F1000Research.
Peer review and advice service hub
Information to support funders to implement the 3Rs and resources for grant applicants.
Primate Welfare Meeting (15 November 2018)
Submit your abstract for this year's Primate Welfare Meeting by Friday 27 July.
Listen to our podcast co-produced with LabAnimal
We have teamed up with LabAnimal to bring you “3 Minute 3Rs”, a monthly podcast summarising the latest 3Rs news.
Public engagement awards scheme: open rolling call
Grant holders can apply for an award of up to £1,500 to engage the public in 3Rs research.
International 3Rs Prize 2017
This year’s 3Rs Prize, sponsored by GSK, was awarded to Dr Elisa Passini for work on computer modelling of cardiotoxicity.
Watch our 'Mouse handling made easy' webinar
Learn the benefits of non-aversive handling methods and tips on how to implement them.
Tickling rats: an enrichment to improve rodent welfare
Exploring a novel technique for refining experiments through social enrichment.
Re-use of needles: is this an indicator of a culture of care?
This guest blog post explores the issue of re-using needles in day-to-day practice.
The 3Rs
We have updated our definitions of the 3Rs so they are more reflective of contemporary scientific practice and developments.
New standards for non-human primate research
We have launched an updated version of our guidelines on accommodation, care and use.
Order hard copies of our resources
Posters and other resources, posted to you (for free) to inform your experimental work.

The NC3Rs

If you are a scientist, animal technician, veterinarian, regulator, funder or policy maker, the NC3Rs can help you to:

  • Drive scientific and technological developments that replace, reduce or refine the use of animals in research (the 3Rs)
  • Ensure your animal experiments are as robust and reproducible as possible
  • Provide the best welfare for laboratory animals


Science-led and evidence-based, we fund research and early careers, foster collaborations between universities and industry to develop and commercialise 3Rs technologies, and provide information on the latest advances to put the 3Rs into practice.

Keep in touch

Latest news & blogs

Six highlights from Pint of Science 2018

We look back at this year's Pint of Science festival, where NC3Rs grantholders spoke about their work in pubs around the country.

British Pharmacological Society launches a new curriculum for the use of research animals

The British Pharmacological Society (BPS) and partner organisations have today launched a new curriculum for undergraduate and taught Masters education on the use of research animals. 

Strategy for the revision of the ARRIVE guidelines

We have published our strategy for the revision of the ARRIVE guidelines, designed to improve the reporting of research using animals.

New Skills and Knowledge Transfer grants awarded

Three awards totalling over £200k have been made in the 2018 NC3Rs Skills and Knowledge Transfer funding competition.

Organs-on-Chips Technology: fostering scientific curiosity to accelerate drug discovery

A new strategic partnership between AstraZeneca and Emulate aims to embed the 3Rs in AstraZeneca's drug discovery programmes through the use of organ-on-a-chip technology.

New platform to maximise the 3Rs impact of NC3Rs-funded research

We have launched the NC3Rs Gateway, a new portal on the F1000Research publication platform dedicated to 3Rs technologies and approaches.