Do you want to adopt a new 3Rs approach or transfer your method to another lab?
Apply for an NC3Rs Skills and Knowledge Transfer Award – submit your informal outline by 4pm on Friday 27 November.
The NC3Rs and the 3Rs during COVID-19
An update on what we are doing to support the research community.
NC3Rs webinars
Register for our upcoming webinars and watch recordings of past presentations on a wide range of 3Rs topics.
2021 Project grant scheme now open
Our flagship scheme funds new 3Rs approaches in any area of medical, biological or veterinary research.
3Rs for the public
Learn more about the 3Rs and their importance in research.
Download the latest Tech3Rs
Our quarterly newsletter for animal technicians can help you discover new ways to put the 3Rs into practice in your facility.
New ARRIVE guidelines 2.0 released
The guidelines and accompanying website will help researchers increase the reliability and reproducibility of animal studies through better reporting.
The 3Rs across Europe: webinar series recordings
Watch talks on the latest 3Rs advances from researchers representing six European 3Rs centres.
Re-starting mouse breeding after lockdown?
Visit our breeding and colony management hub for guidance on re-establishing colonies.
Reducing animal use in the testing of biologicals
New project will review WHO guidelines to identify opportunities to incorporate non-animal testing approaches.
Videos: non-aversive mouse handling in practice
Hear from animal care staff championing non-aversive mouse handling in their facilities.
Experimental design
Resources to help you improve the design and reporting of your in vivo research.

The NC3Rs: Pioneering better science


We help the research community use the latest science and technology to replace animal studies, providing new approaches for biomedical research and avoiding the time and cost associated with in vivo models. Where the use of animals is still required, we support researchers to design the best experiments so that their methods and findings are robust and reproducible. We provide information and guidance on the latest knowledge to improve laboratory animal welfare.

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Latest news

Analysing mouse movement in 3D could bring 3Rs benefits to behavioural tests

Work by NC3Rs Fellow Dr Riccardo Storchi could refine and reduce the use of mice in fields reliant on behavioural analysis.

Refining DNA sampling through skin swabbing in model fish species

New research demonstrates that skin swabbing provides a less invasive method of DNA collection than fin clipping.

Protective cap for macaque cranial implants promotes wound healing

Oxford and Newcastle Universities collaborate to develop a protective cap to promote wound healing in macaques fitted with cranial implants.

Tunnel handling improves the welfare of mice undergoing repeated procedures

Research shows that the welfare benefits of non-aversive handling persist after repeated restraint, IP injection and anaesthesia.