Replacement, Reduction and Refinement
Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
Latest news
Embedding the skills and knowledge needed to develop replacement technologies in the training of early career researchers.
Find out about the work we have funded to build the evidence base for refining the use of fish in research.
Opportunities for the wider adoption of 3Rs approaches within WHO guidance documents for the quality, safety and efficacy of vaccines and biological therapeutics.
Upcoming events
A live demonstration of the Experimental Design Assistant (EDA), online software to help researchers design robust in vivo experiments
A live demonstration of the Experimental Design Assistant (EDA), online software to help researchers design robust in vivo experiments.
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.
