2021 CRACK IT Challenges competition now open
Funding is now available to solve two Challenges involving in silico toxicology and in vitro safety assessment.
Webinar series: Replacing basement membrane extracts
Register now for this upcoming webinar series featuring 3Rs centres from across Europe.
Virtual demonstrations of the EDA
Join our webinars to get started with the Experimental Design Assistant.
Strengthen your 3Rs culture with our self-assessment tools
Our free-to-use tools can help research groups and institutions benchmark their activities and identify new 3Rs opportunities.
The NC3Rs and the 3Rs during COVID-19
An update on what we are doing to support the research community.
NC3Rs webinars
Register for our upcoming webinars and watch recordings of past presentations on a wide range of 3Rs topics.
Download the latest Tech3Rs
Our quarterly newsletter for animal technicians can help you discover new ways to put the 3Rs into practice in your facility.
Animal technician resources
A range of resources to help animal technicians implement the 3Rs.
Evaluating environmental enrichment
A practical resource to support technicians in assessing the impact of new enrichment.
Animal-free in vitro technologies resource
Resources to help you move to animal-free options for more reproducible and reliable experiments.
Visit the NC3Rs gateway
Read detailed 3Rs method articles from our grant holders via our open access portal.
Research culture and the 3Rs
Resources to help you strengthen the research culture of your group or institution through applying the 3Rs effectively.

The NC3Rs: Pioneering better science


We help the research community use the latest science and technology to replace animal studies, providing new approaches for biomedical research and avoiding the time and cost associated with in vivo models. Where the use of animals is still required, we support researchers to design the best experiments so that their methods and findings are robust and reproducible. We provide information and guidance on the latest knowledge to improve laboratory animal welfare.


Find out more: About the 3Rs | About the NC3Rs

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Latest news

£2.9 million awarded to seven new Project grants

Latest funding from the NC3Rs includes awards focused on developing new methods for each of the 3Rs.

Now open for competition: 2021 CRACK IT Challenges announced

Funding now available to solve two Challenges involving computational modelling for new pharmaceuticals and in vitro assays to replace fish in ecotoxicological testing.

Interactive 3Rs self-assessment tools launched

Our free-to-use tools help research groups and institutions to benchmark their 3Rs activities and identify new 3Rs opportunities.

Promoting social housing during telemetry studies

New paper shows social housing is increasingly adopted for dogs, non-human primates and minipigs.