Congratulations to this year's 3Rs Prize winner
Dr Laura Pellegrini (MRC Laboratory of Molecular Biology) was awarded the prize for work on human cerebral organoids.
NC3Rs webinars
Register for our upcoming webinars and watch recordings of past presentations on a wide range of 3Rs topics.
The NC3Rs and the 3Rs during COVID-19
An update on what we are doing to support the research community.
10 years of CRACKing IT
Read about our programme of events celebrating our open innovation programme's first ten years.
Virtual demonstrations of the EDA
Join our webinars to get started with the Experimental Design Assistant.
Listen to "3 Minute 3Rs"
A monthly podcast highlighting the latest 3Rs research, presented by Lab Animal, the North American 3Rs Collaborative and the NC3Rs.
Visit the NC3Rs gateway
Read detailed 3Rs method articles from our grant holders via our open access portal.
Research culture and the 3Rs
Resources to help you strengthen the research culture of your group or institution through applying the 3Rs effectively.
Read our latest blog post on creating a 3Rs legacy
Dr Alasdair Nisbet shares how he maximised the long-term impact of his 3Rs research.
Download the latest Tech3Rs
Our quarterly newsletter for animal technicians can help you discover new ways to put the 3Rs into practice in your facility.
Zebrafish welfare
Opportunities to refine the use of laboratory zebrafish, including common procedures.
Animal technician resources
A range of resources to help animal care staff implement the 3Rs.

The NC3Rs: Pioneering better science


We help the research community use the latest science and technology to replace animal studies, providing new approaches for biomedical research and avoiding the time and cost associated with in vivo models. Where the use of animals is still required, we support researchers to design the best experiments so that their methods and findings are robust and reproducible. We provide information and guidance on the latest knowledge to improve laboratory animal welfare.


Find out more: About the 3Rs | About the NC3Rs

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Latest news

Tackling experimental design in your funding proposal

Tips to avoid common pitfalls when describing your experimental design and methodology with input from our Panel members.

Cerebral organoid model wins 3Rs Prize

Technology has the potential to replace the use of mice in neurological research.

Single use of needles: how AWERBs can support refinements in practice

Dr Sally Robinson (AstraZeneca) explores the role ethical review bodies can play in ensuring refinements such as single use of needles are put into practice.

Replacing animal models of bone degeneration and disuse with a micron-scale organoid

New research from NC3Rs Training Fellow Dr Alexandra Iordachescu on cellular processes in pathological bone loss using a human cell-based organoid model.

Refining non-human primate vaccine studies in the age of COVID-19

A new review paper co-authored by NC3Rs staff sets out opportunities to refine vaccine studies that use non-human primates.