Replacement, Reduction and Refinement
Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
Latest news
New recommendations from the NC3Rs to improve both animal welfare and regulatory efficiency in the UK project licence application and assessment process.
NC3Rs Head of Toxicology Dr Fiona Sewell discusses collaborating with the global toxicology community to reduce and refine animal use in developmental and reproductive toxicity (DART) studies.
The outputs and impacts of a funding call to support a shift away from animal the use of animal derived products.
New NC3Rs recommendations set international standards for designing and reporting in vitro research.
The NC3Rs is supporting technical staff at Newcastle University to drive the uptake of refined mouse pick up methods across UK institutions.
Working with the Only Good Antibodies (OGA) community we have recruited 16 researchers who will drive the validation and use of better antibodies.
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.
