News & blogs


Tackling experimental design in your funding proposal

Tips to avoid common pitfalls when describing your experimental design and methodology with input from our Panel members.

Cerebral organoid model wins 3Rs Prize

Technology has the potential to replace the use of mice in neurological research.


Single use of needles: how AWERBs can support refinements in practice

Dr Sally Robinson (AstraZeneca) explores the role ethical review bodies can play in ensuring refinements such as single use of needles are put into practice.

Replacing animal models of bone degeneration and disuse with a micron-scale organoid

New research from NC3Rs Training Fellow Dr Alexandra Iordachescu on cellular processes in pathological bone loss using a human cell-based organoid model.

Refining non-human primate vaccine studies in the age of COVID-19

A new review paper co-authored by NC3Rs staff sets out opportunities to refine vaccine studies that use non-human primates.

What’s in a legacy? Part 1 – Small acts to make a big impact

Discover how Dr Alasdair Nisbet planned his 3Rs legacy and how it has furthered his research. 

Meet our new Training Fellows

Four new awards will support early career researchers to prepare for an independent career in their chosen 3Rs field.

10 years of CRACKing IT

Celebrating 10 years of our challenge-led, milestone-driven funding competition, CRACK IT Challenges.

New NC3Rs Board members appointed

The five new members bring expertise in animal welfare, neurobiology, glycobiology, systems biology and in vitro toxicology.

ARRIVE guidelines 2.0 now available in six languages

The guidelines are now available in French, German, Chinese, Dutch, Portuguese and Italian.

3Rs citizen science project wins at the 7th Annual Openness Awards

Secret Lives of Mice, developed by MRC Harwell and the NC3Rs, was recognised for engaging the public in animal research.