Dr Nathalie Percie du Sert


Head of Experimental Design and Reporting



Email address


Nathalie leads our work on improving the design of animal research and its reporting in scientific publications. This includes both NC3Rs-funded research and animal research funded elsewhere. She is a member of the Policy and Outreach Group.

View Nathalie's Office-led projects

Other programmes of work

Experimental design

External roles

NC3Rs publications

Percie du Sert N, Hurst V, Ahluwalia A, et al. (2018) Revision of the ARRIVE guidelines: rationale and scope. BMJ Open Science 2018;0:e000002. doi:10.1136/bmjos-2018-000002

Percie du Sert N and Robinson V (2018) The NC3Rs gateway: Accelerating scientific discoveries with new 3Rs models and technologies. F1000Research 7:591. doi:10.12688/f1000research.14964.1

Percie du Sert N, Bamsey I, Bate ST, Berdoy M, Clark RA, Cuthill IC, Fry D, Karp NA, Macleod M, Moon L, Stanford SC, and Lings B (2017) The Experimental Design Assistant. Nature Methods Epub Sept 28, 2017. doi:10.1038/nmeth.4462

Percie du Sert N, Bamsey I, Bate ST, Berdoy M, Clark RA, Cuthill IC, Fry D, Karp NA, Macleod M, Moon L, Stanford SC, and Lings B (2017) The Experimental Design Assistant. PLoS Biology 15:e2003779. doi:10.1371/journal.pbio.2003779

Percie du Sert N, Alfieri A, Allan SM, Carswell HVO, Deuchar GA, Farr TD, Flecknell P, Gallagher L, Gibson CL, Haley MJ, Macleod MR, Mccoll BW, Mccabe C, Morancho A, Moon LDF, O’Neill MJ, Pérez de Puig I, Planas A, Ragan CI, Rosell A, Roy LA, Ryder KO, Simats A, Sena ES, Sutherland BA, Tricklebank MD, Trueman RC, Whitfield L, Wong R & Macrae IM (2017) The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments). J Cereb Blood Flow Metab. doi:10.1177/0271678X17709185

Munafò MR, Nosek BA, Bishop DVM, Button KS, Chambers CD, Percie du Sert N, Simonsohn, U, Wagenmakers, E-J, Ware, JJ and Ioannidis, JPA (2017) A manifesto for reproducible science. Nature Human Behaviour 1: 0021. doi:10.1038/s41562-016-0021

Percie du Sert N, Rice AS (2014) Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain. Br J Pharmacol 171(12): 2951-2963. doi:10.1111/bph.12645

Percie du Sert N, Andrews PL (2014) The Ferret in Nausea and Vomiting Research: Lessons in Translation of Basic Science to the Clinic. In: Biology and Diseases of the Ferret, 3rd edition (Ed. Fox JG, Marini RP) John Wiley & Sons, Inc. doi:10.1002/9781118782699.ch31

Percie du Sert N (2012). Maximising the output of osteoarthritis research: the ARRIVE guidelines. Osteoarthritis and Cartilage 20(4): 253-255 doi:10.1016/j.joca.2011.12.017

Percie du Sert N, Andrews PL, Holmes AM, Wallis R. (2012) Predicting the emetic liability of novel chemical entities: a comparative study. Br J Pharmacol 165(6): 1848-1867. doi:10.1111/j.1476-5381.2011.01669.x

Percie du Sert N (2011) Systematic review and meta-analysis of pre-clinical research: the need for reporting guidelines. Eur Heart J 32(19): 2340. doi: 10.1093/eurheartj/ehr271 

Percie du Sert N (2011) Improving the reporting of animal research: when will we ARRIVE? Dis Model Mech 4(3): 281-282. doi:10.1242/dmm.007971

NC3Rs blogs:

For additional publications, see Nathalie's ResearchGate profile.


PhD, Physiology
St George's University of London, 2005-2009
An investigation in to the mechanism of cisplatin-induced emesis.