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NC3Rs | 20 Years: Pioneering Better Science

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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

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Professor Anthony Chalmers and Co-Investigator Dr Natividad Gomez-Roman have further developed a 3D human cell culture model replacing the use of mice to evaluate and screen treatments for Glioblastoma (GBM).

A group of researchers stand smiling on a sunny day after having paused on a bike ride.

Dr Alan Harper and NC3Rs-BHF PhD student Jacob Ranjbar have developed an artificial human blood vessel to study blood clotting in vitro and replace the use of mice in thrombosis research. They have successfully disseminated the model to the thrombosis community, including for new applications within cardiovascular research.

Portrait of Dr Alan Harper and Dr Jacob Ranjbar

Dr Paola Campagnolo has used NC3Rs funding from a Project grant and a Skills and Knowledge Transfer award to develop an ex vivo model of the epicardium to replace the use of mice for high throughput screening of cardiac therapies in academia and industry.

Dr Paola Campagnolo on the left with three colleagues on the right side of her in a laboratory