Our vacancies

Application of the 3Rs plays an essential role in achieving scientific excellence. The NC3Rs supports the development and uptake of new research tools and models with reduced reliance on the use of animals and/or improved animal welfare. Our activities are divided between our role as a 3Rs research funder and programmes led by our own team of scientists. Additional teams work across the office to support our scientific programmes.

We are currently recruiting for the following role at the NC3Rs:

Programme Manager – Replacement Technologies

Grade: Band 3
Location: London
Salary: £40,016 - £46,643 (plus London allowances)
Contract type: Permanent, full-time

Purpose of the role

The primary purpose of this role is to facilitate an increase in the availability and use of approaches that replace in vivo studies in academia and industry by:

  • Acting as the main point of contact and knowledge holder for replacement science and technology in the NC3Rs helping to raise the visibility of non-animal alternatives in its stakeholder community.
  • Identifying, developing and leading specific projects related to replacement – focusing on the review of research fields and technologies, and the development and implementation of scientific and policy initiatives.
  • Championing the outputs and impacts of NC3Rs research and innovation awards that focus on replacement.

Main duties

  • Horizon scanning for replacement opportunities, including keeping abreast of emerging technologies with replacement potential.
  • Leading expert working groups, preparing reports and papers, and organising scientific events to increase the availability of replacement approaches and support their uptake into day-to-day practice.
  • Establishing relevant networks and partnerships to support the replacement programme.
  • Generating and communicating the evidence base to build confidence in, and raise awareness of, replacement approaches, including representing the NC3Rs at external events nationally and internationally. This includes liaising with the NC3Rs communications team to produce case studies and news articles for use online with scientific and lay audiences.
  • Working with colleagues in the research and innovation funding teams to maximise the NC3Rs investment in replacement approaches, including liaising with award holders.

Person specification




A PhD in a biological science is essential (ideally including in vitro or in silico approaches).

Work experience

Post-doctoral experience is essential ideally in a technology that has the potential to replace the use of animals. An understanding of the barriers/ challenges faced in achieving technology uptake is also desirable. Experience of using various approaches to horizon scan for scientific and technological advances within a field is desirable, as is experience of analysing and summarising research outputs and impacts. The ability to develop, influence and maintain excellent relationships with the full range of NC3Rs scientific stakeholders.

Other experience and knowledge

A comprehensive understanding of the issues around the use of animals in research and a demonstrable commitment to the 3Rs is essential. The role requires the ability to engage with a range of scientific issues and the abilities to assimilate information from a range of sources, think creatively and develop novel solutions to specific challenges and manage a varied workload. Strong organisational and planning skills are essential.

Personal skills,



Excellent oral and written communication skills, close attention to detail and accuracy, and the ability to tailor style and content to a range of scientific, executive and lay audiences is essential. The role requires a team player for collaborative working both within the NC3Rs and externally with stakeholders.

How to apply

The closing date for applications is Thursday 2 September.

Please visit the MRC vacancy portal for further information, including how to apply.

Please ensure you include a copy of your CV and a covering letter. Your cover letter should outline and explain how you meet the criteria listed in the person specification for this position. 

Interviews are due to take in September 2021.