Submitting to the NC3Rs gateway

The gateway was developed to enable our grant holders to publish method articles describing the science and technology emerging from their NC3Rs-funded research in sufficient detail to allow its use by others. Maximising the awareness and adoption of the outputs of NC3Rs-funded grants is vital in achieving our aim of replacing, reducing and refining the use of animals in research.

How to submit | Article types

How to submit to the NC3Rs gateway

1. Contact the NC3Rs office

The NC3Rs gateway is open only to NC3Rs-funded researchers. To submit an article, you must contact the NC3Rs Office or your NC3Rs Regional Programme Manager, where applicable, prior to submission.

2. Incorporate article requirements

The NC3Rs has compiled specific guidance tailored to its gateway and article type formats. NC3Rs staff will provide guidance and advice to grant holders during the drafting process to assist them in aligning their article with the NC3Rs article requirements.

F1000Research advise authors to read their post-publication peer-review model and their policies prior to submission.

3. Submit to the gateway

Articles that have been discussed with the NC3Rs Office and align with the article type requirements can be submitted directly through the NC3Rs gateway.

The NC3Rs will pay for the Article Processing Charges for up to ten articles published on the gateway each year.

Articles can be submitted as Word (DOC or DOCX) or rich text format (RTF) files only. PDF, ZIP or TeX files will not be accepted. LaTeX users can submit via Overleaf, using an F1000Research journal article template.

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What article types can be published on the gateway?

The NC3Rs gateway publishes a number of different article types. The format of article types has been customised to allow the 3Rs, scientific and practical benefits of the work, as well as its current and potential applications to be effectively showcased.

The NC3Rs has compiled specific guidance tailored to its gateway and article type formats to complement the article guidelines provided by F1000Research.

Article types available on the gateway are:

Method Articles

Method Articles describe new and well tested experimental, observational, theoretical or computational methods or procedures, either quantitative or qualitative. This includes new study methods, substantive modifications to existing methods or innovative applications of existing methods to new models or scientific questions. We welcome technical articles that describe tools that facilitate the design or performance of experiments, provide data analysis features or assist medical treatment.

Method Article guidance

Brief Reports

Brief Reports include single-finding papers that can be reported with one or two illustrations (figures/tables), descriptions of unexpected observations, and lab protocols. Posters from conferences or internal meetings may be summarised as Brief Reports. In many cases, some additional detail, particularly in the methods, description of the results, and/or discussion/ conclusions will be required to make sure that readers (and reviewers) have enough information to understand the description of the work.

Brief Report guidance

Data Notes

Data Notes are brief descriptions of datasets that promote the potential reuse of research data and include details of why and how the data were created; they do not include any analyses or conclusions.

Data Note guidance

Software Tool Articles

A Software Tool Article should include the rationale for the development of the tool and details of the code used for its construction. The article should provide examples of suitable input data sets and include an example of the output that can be expected from the tool and how this output should be interpreted.

Software Tool guidance


Reviews should provide a balanced and comprehensive overview of the latest discoveries in a particular field.

Review guidance

Registered Reports

Registered Reports are a form of empirical article in which the methods and proposed analyses are published and reviewed prior to research being conducted. This format of article seeks to address a number of inappropriate research practices, including flaws with the study design, and selective reporting of results. Further information on Registered Reports can be found on F1000Research.

Registered are prepared in two stages:

Please note that Study Protocols and Research Articles will only be accepted on the NC3Rs gateway as part of a Registered Report.