Here we provide a summary of what you can expect from the NC3Rs as your funding body, but also some of our expectations of our grant holders. You can also find information about managing your NC3Rs grant for its duration. If you have any questions that are not answered on these pages, please contact the NC3Rs funding team.
The grant holder information page is split into the following sections:
For the 3Rs impacts of a project to be realised we need our grant holder's work to be disseminated and taken up by the wider researcher community. We want to develop and maintain strong and collaborative relationships with our grant holders to enable this to happen. We will have various interactions with you throughout the lifetime of your award. The main points of interaction are:
Introductory phone call (0 - 3 months)
We will call you within two months of your award start date, to make sure there have been no complications preventing the award starting.
Grant holder visit (mid point of award)
Halfway through your award, the funding team Programme Manger(s) will contact you to organise the meeting and send a project progress form to be completed, which informs discussion during the meeting.
This meeting is used to identify where our expertise/networks could help maximise your project's impacts, any NC3Rs further funding opportunities available, and assess the project's progress compared to the 3Rs and scientific objectives.
Our Board members may also attend these meetings to gain insights into the research we fund.
Progress update by phone or visit (end of award)
We will call/visit within six months of the end of the award. This update aims to follow up on the outcomes and outputs of the project and where any further opportunities exist to achieve 3Rs impact.
Post award amendments, including extensions and changes to the project, should be first discussed with the NC3Rs funding team in all cases by emailing firstname.lastname@example.org.
The NC3Rs does not routinely extend awards, except for maternity leave, gaps in employment or staggered start dates. In exceptional circumstances, we may consider extending the grant.
The delays or shortfall must seriously threaten the delivery of a significant proportion of the science outlined in the original application. Applicants must be able to demonstrate the delays could not have been anticipated, were outside their control and every effort has already been made to mitigate them.
With the exception of multiple periods of maternity/paternity/sick leave, a grant will be allowed no more than one extension. If an extension has already been approved, further requests will not normally be considered.
Requests for additional funds will only be considered in exceptional circumstances.
Changes to an NC3Rs-funded project
Grant holders must inform and consult with the NC3Rs if there are any significant changes that may affect the progress or delivery of the project and its potential to realise a 3Rs impact. No substantive changes to the experimental design of a project involving the use of animals, which might affect the ethical characteristics of the award, are allowed without prior approval from the NC3Rs.
If a grant holder proposes to make significant changes to their NC3Rs-funded project, we reserve the right to request revised proposals for approval. Where significant changes are proposed, the NC3Rs may decide to make a new grant in place of the existing grant, or to revise, retain or terminate the existing grant.
Grant holders should report on the outputs and outcomes of the research we have funded on a regular basis, including after the lifetime of the award. In line with UKRI, we use Researchfish to collect this information, including an annual mandatory submission period.
A summary of outputs and impacts as reported by our grant holders in the 2018 researchfish® submission period can be accessed here. Please note clicking this link will download a pdf file.
Log-in details are provided by Researchfish Ltd. Failure to submit during the mandatory submission period may result in sanctions preventing the grant holder applying for UKRI awards until a submission during the next period is made. Information in Researchfish should also be updated shortly before the grant is due to end. Failure to update within three months of the grant end date will result in an automatic financial penalty.
We reserve the right to sanction a grant at any stage if unsatisfactory progress has been made.
We want to help maximise the impact of your research, including any publications or other material arising from an NC3Rs award. We can only do this with appropriate notice, allowing time to prepare publicity material. Ideally, inform us pre-publication by emailing a PDF copy of your manuscript to email@example.com.
We also have the following expectations of publications arising from NC3Rs funding:
It is a missed opportunity if publications from NC3Rs-funded grants are being published without the 3Rs impacts being discussed.
All publications arising from NC3Rs funding should:
- Make reference to the 3Rs implications of the research, including in the abstract and the main body of the text
- Be reported in accordance with the the ARRIVE guidelines, taking into account the specific editorial policies of the journal concerned
For 3Rs models and approaches to be taken up, specific information regarding the impacts, methodological and technological details, performance characteristics and comparison to the current gold standard is needed in the public domain.
We require the methods from each grant to be published, either in the NC3Rs gateway or another relevant methods journal. These publications should include enough technical detail for other researchers in the field to make an informed decision as to whether the 3Rs model/tool/approach are appropriate for their research.
We expect NC3Rs grant holders to disseminate their results by publishing in appropriate scientific journals, which are compliant with the UKRI open access of publications policy. The NC3Rs contribution to Article Processing Charges (APCs) will be paid for via the MRC contribution to the RCUK block grant. Any publication arising from NC3Rs-funded research should be deposited into Europe PubMed Central at the point of publication or within six months at the latest and included in your Researchfish grant record.
We follow UKRI policy and support the principles of the Concordat on Open Research Data, which recognises that research data should be made openly available for use by others wherever possible in a manner consistent with relevant legal, ethical, disciplinary and regulatory frameworks and norms, and with due regard to the cost involved.
Guidance text for acknowledging the NC3Rs:
'We thank the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) for funding this work ([insert grant number] to [insert author(s) initials]). Article processing charges were paid from the Medical Research Council contribution to the RCUK block grant to [insert name of institution].'
The terms and conditions of your NC3Rs grant will be set out in your award letter. For reference, the terms and conditions relevant to each grant type are as follows:
|NC3Rs grant||Terms and Conditions|
|Skills and Knowledge Transfer grant||
NC3Rs-funded researchers must also abide to the following guidance and guidelines:
- Implement the principles in the cross-funder guidance Responsibility in the Use of Animals in Bioscience Research
- Where non-human primates are used, implement the principles in the NC3Rs guidelines Primate Accommodation, Care and Use
- Abide by the UKSBS/NC3Rs policy on preferred suppliers of antibodies
Here we list a number of links to other pages of the NC3Rs website that may be helpful for our grant holders: