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NC3Rs | 20 Years: Pioneering Better Science

Latest news from the NC3Rs: September 2022

2022 CRACK IT Challenges: Open for applications

CRACK IT Challenges focus on developing products and services that deliver scientific and 3Rs benefits in key areas of research. This year’s Challenges have been set by industrial Sponsors and the NC3Rs and are now open for applications:

  • T‑ALERT: Animal‑free tumourigenicity assessment of CAR‑T and other genetically modified T cells.

    Application deadline: Thursday 27 October, 12.00 (BST)
  • Thyroid Tox: Development of an in silico model to predict thyroid receptor mediated human endocrine disruption.

    Application deadline: Thursday 3 November, 12.00 (GMT)

Visit the NC3Rs Innovation platform for more details of each Challenge, as well as application forms and links to join our LinkedIn groups for networking and consortia building.

Six NC3Rs Project grants to support new 3Rs technologies

We have awarded six new Project grants totalling over £2.8M, bringing the total number of grants awarded under this scheme to over 150. The majority of the projects awarded this round focus on replacement technologies, reflecting the current landscape for 3Rs research and increasing interest in alternatives to in vivo research, as highlighted in our recent Strategy.

Workshop: Implementing the 3Rs in WHO guidelines – Understanding the impact on quality control and batch release testing of biologicals in Pan-America

Monday 26 September, 13:00 – 18:00 (BST)


This workshop is the latest in a series for biologicals manufacturers, regulators and other relevant stakeholders around the world to share their perspective on how wider application of the 3Rs could impact the quality control and batch release testing of biologicals. The outputs from these workshops will inform recommendations we make to the WHO on implementing the 3Rs in their guidelines.

An additional workshop for Africa will take place later in 2022; recordings of the sessions from workshops focusing on Europe and Asia are available on the NC3Rs website.

Webinar: Sharp and to the Point – A precise, low dead space needle with improved animal welfare

Wednesday 12 October, 14.00 – 15.00 (BST)


This webinar will focus on the development of the Precision Injection System by Active Needle Technology Ltd. The technology was developed as part of a CRACK IT Challenge to improve the preclinical injections of rodents, enabling high accuracy and precision injection, and refining the delivery of substances using single-use needles to improve animal welfare.

Join us to learn more about the Precision Injection System, its application and the scientific, business and animal welfare benefits of the technology.

Primate Welfare Meeting: Programme available

Tuesday 8 November, 12.00 – 17.45 (GMT)

Central London/online (hybrid)

The programme for this year’s Primate Welfare Meeting features a range of presentations and posters on topics from breeding and husbandry to research use and welfare assessment. Attendees are encouraged to join in‑person to take advantage of the networking opportunities, but delegates will be able to view the live stream remotely to ensure the sessions are available to the global community.

If you are a researcher, veterinarian, technician or facility manager working directly with laboratory non‑human primates, be sure to register and reserve your place.

Virtual demonstrations of the Experimental Design Assistant

Tuesday 22 November, 16.00 – 17.00 (GMT)


Our Experimental Design Assistant (EDA) tool can help researchers at any level design robust in vivo experiments. Following a presentation on the key aspects of the online tool, Dr Esther Pearl (NC3Rs Experimental Design Programme Manager) will answer questions on how you can use the EDA to design and plan your next study. Limited spaces are available on a first come first served basis.

Closing soon: 2022 IAT Andrew Blake Tribute Award

Are you an animal technician, and have you or your team refined animal care and welfare in your facility? Don’t keep your good idea to yourself! This year’s Institute of Animal Technology (IAT) Andrew Blake Tribute Award is open for applications from technicians at any stage of their career primarily working in the UK. You have until Friday 30 September to get your entry in, so don’t miss this opportunity to be recognised for your hard work.

Last chance to apply for the 2022 EPAA 3Rs Science Prize

Every two years the European Partnership for Alternatives to Animal Testing (EPAA) awards their 3Rs Science Prize to a researcher who has made an outstanding contribution to the 3Rs within regulatory testing. This year’s call for applications is now open – scientists from both industry and academia with up to ten years' postgraduate experience are encouraged to apply.

Applications should be sent to by Monday 3 October, 12.00 (CEST).

Register for upcoming LASA meetings

The Laboratory Animal Science Association (LASA) holds regular meetings relevant to those working directly with research animals. Upcoming meetings include:

  • LASA 3Rs Section/UFAW Meeting: Stitching the 3Rs into surgical procedures

    Tuesday 27 September, Stevenage
  • RSPCA/LASA/LAVA/IAT AWERB-UK meeting, focused on induction and training for all AWERB members

    Thursday 6 October, Birmingham
  • LASA Home Office Liaison, Training and Information Forum Meeting

    Monday 10 October, online
  • LASA Annual Conference

    Tuesday 22 and Wednesday 23 November, Birmingham

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