TruLarv Galleria mellonella - a model host for infection studies, toxicity testing and drug development (Partnering with Demuris) Contractor: Dr Olivia Champion, CRACK IT Solution
TruLarv Galleria mellonella - a model host for infection studies, toxicity testing and drug development (Partnering with Envigo) Contractor: Dr Olivia Champion, CRACK IT Solution
Human tissue models for lung disease Principal Investigator: Professor Maria Belvisi, Imperial College London Infrastructure grant
Developing a zebrafish model of neurovascular coupling (NVC) Principal Investigator: Dr Clare Howarth, University of Sheffield Project grant
Developing alternative models to evaluate the impact of nanomaterials on neutrophils during the stimulation and resolution of inflammation Principal Investigator: Dr Helinor Johnston, Heriot-Watt University Project grant
Cas9 mediated in vitro gene editing in primary mammary epithelial cells Principal Investigator: Dr Walid Khaled, University of Cambridge PhD Studentship
Reducing animal use in thrombosis research with an ex vivo injury model Principal Investigator: Dr Matthew Harper, University of Cambridge PhD Studentship
Developing an Organ on a Chip Model to Test the Therapeutic Efficacy of Adhirons in Breast Cancer Principal Investigator: Dr Darren Tomlinson, University of Leeds PhD Studentship
Development of functional 3D human intestinal mucosae to replace rodent models and improve the predictive accuracy of existing in vitro systems Principal Investigator: Professor Stefan Przyborski, Durham University PhD Studentship
Developing a Drosophila melanogaster model of the cardiac myocyte action potential to investigate function and performance Principal Investigator: Dr Jeremy Niven, University of Sussex PhD Studentship
Reducing animal usage in antifungal drug development: iRFP reporter strains and imaging infection Principal Investigator: Dr Donna MacCallum, University of Aberdeen PhD Studentship
Developing Human Glioma OrganDot Cultures Principal Investigator: Professor William Gray, Cardiff University PhD Studentship
Refining an in vitro system of predictive biomarkers of in vivo liposome efficacy Principal Investigator: Dr Andrew Devitt, Aston University PhD Studentship
Refinement of hematopoietic cell transplantation using optical imaging in zebrafish Principal Investigator: Professor Margaret Dallman, Imperial College London PhD Studentship
Using zebrafish for pre-clinical brain haemorrhage research Principal Investigator: Professor Stuart Allan, University of Manchester PhD Studentship
Reducing the use and refining the distribution of male Xenopus Principal Investigator: Professor Matthew Guille, University of Portsmouth Infrastructure grant
Building brains in a dish - using ES cells to understand brain development Principal Investigator: Dr John Mason, University of Edinburgh PhD Studentship
Improving biological integration of osseous and dermal tissues in macaque cranial implants Principal Investigator: Professor Alex Thiele, Newcastle University Strategic grant
In silico human-based methodologies for evaluation of drug cardiac safety and efficacy Principal Investigator: Professor Blanca Rodriguez, University of Oxford Infrastructure grant
Metaboderm: 3D hiPSC derived skin model and in-silico skin modelling of metabolism Contractor: Newcells Biotech Ltd, CRACK IT Challenge