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Development of a Drosophila-based platform to replace and reduce animal experimentation in epilepsy research

Institution: 

  • King's College London
  • Project grant

Using a novel, high welfare in vivo feeding device for poultry red mite and its integration with other novel tools for this parasite

Institution: 

  • Moredun Research Institute
  • Skills and Knowledge Transfer grant

Sharing new non-invasive circadian phenotyping methods

Institution: 

  • University of Oxford
  • Skills and Knowledge Transfer grant

Naturally sterile hybrid mice for the production of embryo transfer recipients

Institution: 

  • University of Oxford
  • Skills and Knowledge Transfer grant

Establishment of novel macrophage cell lines to study the pathogenesis of respiratory bacterial pathogens in lung alveolar macrophages

Institution: 

  • University of Plymouth
  • Skills and Knowledge Transfer grant

WaterR: A tool for better management and monitoring of rodent fluid intake

Institution: 

  • University of Bristol
  • Skills and Knowledge Transfer grant

Sharp and to the Point: Developing a device for injections in mice that avoids the re-use of needles

  • CRACK IT Challenge

MacuSIM: A microfluidic, in vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials

Institution: 

  • University of Southampton
  • Fellowship

A novel embryonic zebrafish model to replace mammals in the study of 3-hydroxyacyl CoA dehydratase 1-associated muscle disorders

Institution: 

  • University of Liverpool
  • Fellowship

Modelling radiobiology effects of X-rays in small laboratory animals to develop guidelines for preclinical computed tomography imaging

Institution: 

  • University of Edinburgh
  • Fellowship

A computational framework to investigate the mechanical role of the extracellular matrix in tissue development and disease

Institution: 

  • University College London
  • Fellowship

Development of non-mammalian, preclinical screening tools for the predictive analysis of cardiotoxicity

Institution: 

  • University of East Anglia
  • PhD Studentship

Use of induced pluripotent stem cell derived cardiomyocytes to test the consequences of genetic variants in atrial and ventricular arrhythmias

Institution: 

  • University of Birmingham
  • PhD Studentship

INDUCE-seq: a novel tool for next generation risk assessment

Institution: 

  • Cardiff University
  • PhD Studentship

Developing an in silico, spectroscopic imaging toolkit for assessing skin penetration

Institution: 

  • University of Surrey
  • PhD Studentship

An improved C. elegans model of Alzheimer's disease to monitor neuronal signalling activity

Institution: 

  • University of Leeds
  • PhD Studentship

Modelling O-GlcNAc transferase intellectual disability syndrome in Drosophila

Institution: 

  • University of Dundee
  • PhD Studentship

A 3Rs approach to assess drug toxicity on the mammalian embryo during early pregnancy in vitro

Institution: 

  • University of Liverpool
  • PhD Studentship

Direct replacement of secondary antibodies by Affimer proteins

Institution: 

  • University of Leeds
  • PhD Studentship

A next generation Quiescence and Cell Cycle Indicator for the refinement and reduction of animal usage in proliferation assays

Institution: 

  • Lancaster University
  • PhD Studentship

3D bio-printing human pluripotent stem cell-derived skeletal muscle constructs for disease modelling and drug discovery

Institution: 

  • Queen Mary University of London
  • PhD Studentship

Ex vivo drug screening using human tissue to personalise cancer therapy and replace murine avatars

Institution: 

  • University of Sheffield
  • PhD Studentship

A novel tool that embeds 3Rs principles in multiple sclerosis research

Institution: 

  • University of Glasgow
  • PhD Studentship

A living biobank of post-surgical residual glioblastoma to replace animal studies

Institution: 

  • University of Sheffield
  • PhD Studentship

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