Studentship vacancies

Why do an NC3Rs-funded PhD?

  • Gain a solid introduction to research that aims to replace, reduce and refine the use of animals in science.
  • Undertake scientific training with a prestigious university committed to 3Rs research.
  • Join the UK's growing 3Rs research community and participate in our studentship summer school.
  • Contribute to research that advances the boundaries of how science is conducted.


Candidates should hold, or realistically expect to obtain, at least an Upper Second Class Honours degree or equivalent. They should have a strong academic background in the biological sciences and a desire to pursue research in line with that of the research groups. Requirements vary for each studentship.

Posts are open to UK nationals. EU nationals, who have spent at least 3 years prior to the application resident in the UK, are also eligible to apply. Non-UK residents can only be considered if the Research Organisation can demonstrate a shortage of high-quality UK candidates, and this must be approved by the NC3Rs prior to appointment.

Funding provides full support for tuition fees for the three-year duration of the studentship, associated project costs, and an annual tax-free stipend. The national minimum doctoral stipend is set annually by RCUK, for 2017/18 - £14,553. In line with the MRC, NC3Rs sets a higher minimum stipend level for inside London, for 2017/18 - £16,553.

Current vacancies

14 three-year PhD studentships are being funded by the NC3Rs, three of which are jointly funded with BHF. All the studentships are due to commence in 2018. For further information, details of the application process and deadlines for submission, please contact the relevant project supervisor:

University of Birmingham
Replacing animal models in fungal pathogen research: An in vitro Titan virulence assay for the human fungal pathogen Cryptococcus neoformans
Supervisor: Dr Elizabeth Ballou

University of Cambridge
Moving the adverse outcome pathways framework towards practical utility by integrating compound profiling data and using deep learning
Superviser: Dr Andreas Bender

Queen's University of Belfast
Refinement of soft tissue targeting and alignment protocols is small animal radiotherapy using an injectable fiducial marker
Supervisor: Dr Karl Butterworth

University of Sheffield
Using zebrafish embryos to identify genes that protect against artheosclerosis (joint award with the BHF)
Supervisor: Professor Paul Evans

Zoological Society London, Institute of Zoology
Refining, reducing and replacing non-model amphibian experiments on amphibian infectious diseases
Supervisor: Dr Trenton Garner

Keele University
Recreating thrombosis models using tissue-engineered arterial constructs: A novel method to reduce and replace mice used in platelet research (joint award with the BHF)
Supervisor: Dr Alan Harper

Swansea University
Developing an in vitro repeat-dose test as a 3Rs approach to detect non-genotoxic carcinogens
Professor Gareth Jenkins

University of Birmingham
Developing and validating a computational model of the gut microbiota-mucosa interactions to replace and reduce animal experiments
Dr Jan-Ulrich Kreft

Imperial College London
Galleria mellonella - a novel infection model for Mycobacterium tuberculosis aimed at reducing the number of animals in experimentation
Professor Paul Langford

John Innes Centre
Insects as models to study the impact of antibiotics and microbiota therapies on the human gut microbiome: reducing the use of animals in research
Professor Anthony Maxwell

University College London
Generating in vitro human optic vesicles to dissect the genetic modifiers affecting ocular maldevelopment
Supervisor: Dr Mariya Moosajee

University of Exeter
An alternative approach for assessing drug-induced seizures, using non-protected larval zebrafish
Supervisor: Professor Charles Tyler

University of Sussex
Characterising Mycobacterium tuberculosis in the human lung; developing new tools for antimicrobial drug discovery through the SH-TBL clinical trial
Supervisor: Dr Simon Waddell

Manchester Metropolitan University
Development of E-Sense: a flexible in vitro platform to determine cardiovascular risk (joint award with the BHF)
Supervisor: Dr Stephen White