InMutaGene: A human IPS cell model for gene therapy vector safety evaluation Contractor: GeneWerk GmbH, CRACK IT Challenge
A new Drosophila-based strategy to study mitochondrial transport and neuronal ageing in vivo Principal Investigator: Dr Alessio Vagnoni, Fellowship
Murinised Firefly Luciferase: A new direction towards immune-shielding and biological relevance Principal Investigator: Professor James Murray, Cardiff University PhD Studentship
Development of a novel cell based bitter taste assessment assay Principal Investigator: Dr Afzal Rahman Mohammed, Aston University PhD Studentship
Comprehensive target screening by label-free cell microarray profiling to reduce animal efficacy and toxicology studies in drug discovery Contractor: Dr James Sidaway, CRACK IT Solution
A bovine alveolus model to replace cattle in the study of host-pathogen interactions in bovine tuberculosis Principal Investigator: Professor Mark Chambers, University of Surrey Strategic grant
Microfluidic networks: an in vitro 3D culture system for the investigation of neuron-glial interactions in neurodegeneration Principal Investigator: Dr Tomas Bellamy, University of Nottingham PhD Studentship
Development and validation of a rodent touchscreen battery for assessing motivation and affective state Principal Investigator: Dr Lisa Saksida, University of Cambridge Project grant
A multi-cellular 3D model of human breast tissue to replace rodent xenograft models in breast cancer research Principal Investigator: Professor Cathy Merry, University of Nottingham Project grant
Development and characterisation of a human ex vivo model of aneurysm Principal Investigator: Dr Jason Johnson, University of Bristol PhD Studentship
Portable bioluminescence test for botulinum neurotoxin Contractor: Dr Gregory Stevens, CRACK IT Solution
Review of the use of two species in regulatory toxicology studies Current contact: Dr Elisa Passini, Office-led project
Probing in vivo parasite biology in vitro Principal Investigator: Professor Aaron Maule, Queen's University Belfast Project grant
Modelling liver fibrosis using human Induced Pluripotent Stem Cells Principal Investigator: Dr Ludovic Vallier, University of Cambridge Project grant
Development of a 3D mouse atlas tool for improved non-invasive imaging of orthotopic mouse models of pancreatic cancer Principal Investigator: Dr Jane Sosabowski, Queen Mary University of London PhD Studentship
Developing tools for functional assessment of a milder model of stroke Principal Investigator: Dr Rebecca Trueman, University of Nottingham PhD Studentship
Using proxy measures of a depressive-like state to assess the impact of pre-clinical models of chronic diseases on the welfare of mice Principal Investigator: Dr Tom Smulders, Newcastle University PhD Studentship
An organotypic model of bronchial dysplasia Principal Investigator: Dr Frank McCaughan, University of Cambridge PhD Studentship
Improving the welfare and monitoring of rodents undergoing experimental stroke studies Principal Investigator: Dr Claire Gibson, University of Leicester PhD Studentship