Information and guidance on replacing animal-derived reagents and products to improve reproducibility and reduce animal use.
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Information to help refine the housing and husbandry of the laboratory rabbit.
Resources and information on the innovative technologies available to replace animal-derived scaffolds.
Information to help refine the housing and husbandry of the laboratory cat.
Information to help refine the housing and husbandry of the laboratory rat.
The positive impact playpens have on laboratory rat welfare, and guidance on how to set one up in your institution.
Information to help refine the housing and husbandry of the laboratory guinea pig.
Guidance document on opportunities to reduce and refine the use of GA mice through cryopreservation and sharing.
Reducing and refining acute toxicity tests in the pharmaceutical and chemicals industries.
Providing an evidence base to refine and reduce the use of vertebrates in (regulatory) ecotoxicology studies
Using exposure science to refine and reduce animal use, and support the uptake of new approach methodologies
Supporting the uptake of new approach methodologies to reduce reliance on traditional animal toxicity tests
Guidance on reducing or refining animal use for studies with cardiovascular, central nervous system and respiratory functional measurements.
Projects providing guidance to reduce animal use or refine procedures within toxicology studies.
10 years of CRACK IT webinar: The Human In Vitro Gene Therapy Genotoxicity Testing service.
A webinar exploring how environmental monitoring can replace the use of sentinel animals for monitoring mouse colonies for the presence of pathogens.
A webinar series from a cross-European group of 3Rs centres exploring the challenges and opportunities of replacing BMEs.
Information to help refine the housing and husbandry of the laboratory hamster.
The evidence supporting the use of tunnel and cup handling to improve animal welfare and scientific outcomes (presented at AALAS 2021).
Details of the Rat Grimace Scale, including a poster for display in laboratory rooms and corridors.
Details of the Mouse Grimace Scale, including a poster for display in laboratory rooms and corridors.
Information to help refine the housing and husbandry of the laboratory mouse.
10 years of CRACK IT webinar: An IVF micro microfluidic device for non-surgical embryo transfer to generate transgenic mice.
Information to help refine the housing and husbandry of the laboratory dog.