Dr Rickie Patani from the Francis Crick Institute and UCL Queen Square Institute of Neurology led a multidisciplinary team in developing a model that avoids the use of animals.

Our latest Research Review profiles the work of 12 NC3Rs-funded scientists, exploring its impacts beyond the 3Rs.

Take this opportunity to ask questions about refined mouse handling methods and share your experiences via #3Rschat.

We have awarded a total of £460k to four talented 3Rs-minded postdoctoral researchers to support the development of their careers.

Read our new report, co-produced with Medicines Discovery Catapult and the University of Liverpool MRC Centre for Drug Safety Science.

This award, made through our CRACK IT Challenges programme, will support the development of a more human-relevant platform for DART testing.

Learn more about how our peer review and advice service helps funders and grant applicants to implement the 3Rs as we reach the milestone of 1,000 completed reviews.

Could your organisation sponsor the next CRACK IT Challenge to improve R&D and reduce reliance on animal models?

From the important role of statistics in implementing the 3Rs to celebrating female researchers, we look back at our most popular news stories and blog posts from the past year.