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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

Activity type

Topic

Model

533 results

Combinatorial mathematical modelling & novel toxicological profiling of drug-induced hepatotoxicity

Principal Investigator: Dr John Ward Loughborough University

PhD Studentship

Developing a novel model to assess the specificity of appetite-reducing agents

Principal Investigator: Dr Kevin Murphy Imperial College London

PhD Studentship

A collection of test tubes containing coloured liquid

Feasibility of replacing invasive heart pressure measurements with non-invasive MR Elastography to reduce rodent numbers in pre-clinical research

Principal Investigator: Dr Jurgen Schneider University of Oxford

Pilot study grant

A stock image of round glass dishes containing blue and green liquid arranged closely together.

Assessing welfare in fish: the answer is in the water!

Principal Investigator: Dr Ioanna Katsiadaki Centre for Environment Fisheries and Aquaculture Science

Project grant

Human and mouse artificial lymph nodes: novel technology to reduce and replace the use of animal models in clinical and developmental immunology

Principal Investigator: Dr Mark Coles University of York

Project grant

Refinement of the use of fluid control as a motivational tool for non-human primates in neuroscience research

Principal Investigator: Professor Alex Thiele Newcastle University

PhD Studentship

The development of an in vitro model of spinal cord injury to study aligned neurite outgrowth

Principal Investigator: Professor Susan Barnett University of Glasgow

PhD Studentship

Professor Susan Barnett in the laboratory

Characterisation and validation of an organotypic slice culture model of Alzheimer’s disease

Principal Investigator: Dr Wendy Noble King's College London

PhD Studentship

Development of a non-animal model for characterizing drug-resistant tumours

Principal Investigator: Professor Catherine Pears University of Oxford

PhD Studentship

Microscope view of Dictyostelium slime mold

A Drosophila model of Candida albicans gastrointestinal infection

Principal Investigator: Professor Petros Ligoxygakis University of Oxford

PhD Studentship

Bone healing and regeneration in an ex vivo bioreactor – evaluation of angiogenesis and reparation for clinical application

Principal Investigator: Professor Richard Oreffo University of Southampton

PhD Studentship

In vitro and in silico models of gut bacterial diversity and its impacts on human health

Principal Investigator: Professor Timothy Barraclough Imperial College London

PhD Studentship

Development of non-radioactive labels for a receptor binding assay for paralytic shellfish poisoning (PSP) toxin testing

Principal Investigator: Professor Christopher Elliott Queen's University Belfast

PhD Studentship

Optimisation of a flow-based human in vitro blood–brain barrier model to replace animal models for studying immunopathogenesis of viral brain infections

Principal Investigator: Dr Adjanie Patabendige University of Liverpool

Fellowship

Reducing animal dependency in diabetes research through pancreatic stem cells

Principal Investigator: Professor Mark Dunne University of Manchester

PhD Studentship

Construction of a miniaturised human lymph node model as an alternative to the Local Lymph Node Assay

Principal Investigator: Professor Amir Ghaemmaghami University of Nottingham

PhD Studentship

Reduction & refinement in animal models of neuropathic pain: using systematic review & meta-analysis

Principal Investigator: Dr Emily Sena University of Edinburgh

Project grant

Using induced pluripotent stem cells as a replacement for in vivo models to screen novel therapies which target self-renewal pathways in chronic myeloid leukaemia

Principal Investigator: Dr Helen Wheadon University of Glasgow

PhD Studentship

Refining, reducing and replacing in vivo WHO-standard preclinical assays of snake venom pathology and antivenom efficacy

Principal Investigator: Dr Robert Harrison Liverpool School of Tropical Medicine

PhD Studentship

Developing an integrated "in vitro carcinogenicity predictive tool" utilising in vitro cell signalling and cell behaviour assessment coupled with in vitro genotoxicity data

Principal Investigator: Professor Gareth Jenkins Swansea University

Strategic grant