Combinatorial mathematical modelling & novel toxicological profiling of drug-induced hepatotoxicity Principal Investigator: Dr John Ward Loughborough University PhD Studentship
Developing a novel model to assess the specificity of appetite-reducing agents Principal Investigator: Dr Kevin Murphy Imperial College London PhD Studentship
Feasibility of replacing invasive heart pressure measurements with non-invasive MR Elastography to reduce rodent numbers in pre-clinical research Principal Investigator: Dr Jurgen Schneider University of Oxford Pilot study grant
Assessing welfare in fish: the answer is in the water! Principal Investigator: Dr Ioanna Katsiadaki Centre for Environment Fisheries and Aquaculture Science Project grant
Human and mouse artificial lymph nodes: novel technology to reduce and replace the use of animal models in clinical and developmental immunology Principal Investigator: Dr Mark Coles University of York Project grant
Refinement of the use of fluid control as a motivational tool for non-human primates in neuroscience research Principal Investigator: Professor Alex Thiele Newcastle University PhD Studentship
The development of an in vitro model of spinal cord injury to study aligned neurite outgrowth Principal Investigator: Professor Susan Barnett University of Glasgow PhD Studentship
Characterisation and validation of an organotypic slice culture model of Alzheimer’s disease Principal Investigator: Dr Wendy Noble King's College London PhD Studentship
Development of a non-animal model for characterizing drug-resistant tumours Principal Investigator: Professor Catherine Pears University of Oxford PhD Studentship
A Drosophila model of Candida albicans gastrointestinal infection Principal Investigator: Professor Petros Ligoxygakis University of Oxford PhD Studentship
Bone healing and regeneration in an ex vivo bioreactor – evaluation of angiogenesis and reparation for clinical application Principal Investigator: Professor Richard Oreffo University of Southampton PhD Studentship
In vitro and in silico models of gut bacterial diversity and its impacts on human health Principal Investigator: Professor Timothy Barraclough Imperial College London PhD Studentship
Development of non-radioactive labels for a receptor binding assay for paralytic shellfish poisoning (PSP) toxin testing Principal Investigator: Professor Christopher Elliott Queen's University Belfast PhD Studentship
Optimisation of a flow-based human in vitro blood–brain barrier model to replace animal models for studying immunopathogenesis of viral brain infections Principal Investigator: Dr Adjanie Patabendige University of Liverpool Fellowship
Reducing animal dependency in diabetes research through pancreatic stem cells Principal Investigator: Professor Mark Dunne University of Manchester PhD Studentship
Construction of a miniaturised human lymph node model as an alternative to the Local Lymph Node Assay Principal Investigator: Professor Amir Ghaemmaghami University of Nottingham PhD Studentship
Reduction & refinement in animal models of neuropathic pain: using systematic review & meta-analysis Principal Investigator: Dr Emily Sena University of Edinburgh Project grant
Using induced pluripotent stem cells as a replacement for in vivo models to screen novel therapies which target self-renewal pathways in chronic myeloid leukaemia Principal Investigator: Dr Helen Wheadon University of Glasgow PhD Studentship
Refining, reducing and replacing in vivo WHO-standard preclinical assays of snake venom pathology and antivenom efficacy Principal Investigator: Dr Robert Harrison Liverpool School of Tropical Medicine PhD Studentship
Developing an integrated "in vitro carcinogenicity predictive tool" utilising in vitro cell signalling and cell behaviour assessment coupled with in vitro genotoxicity data Principal Investigator: Professor Gareth Jenkins Swansea University Strategic grant