Optimising liver equivalents to model liver fibrosis Principal Investigator: Dr Fiona Oakley, Newcastle University Pilot study grant
The detection, assessment and alleviation of pain in laboratory zebrafish Principal Investigator: Dr Lynne Sneddon, University of Liverpool Project grant
Combinatorial mathematical modelling & novel toxicological profiling of drug-induced hepatotoxicity Principal Investigator: Dr John Ward, Loughborough University PhD Studentship
Developing a novel model to assess the specificity of appetite-reducing agents Principal Investigator: Dr Kevin Murphy, Imperial College London PhD Studentship
Feasibility of replacing invasive heart pressure measurements with non-invasive MR Elastography to reduce rodent numbers in pre-clinical research Principal Investigator: Dr Jurgen Schneider, University of Oxford Pilot study grant
Assessing welfare in fish: the answer is in the water! Principal Investigator: Dr Ioanna Katsiadaki, Centre for Environment Fisheries and Aquaculture Science Project grant
Human and mouse artificial lymph nodes: novel technology to reduce and replace the use of animal models in clinical and developmental immunology Principal Investigator: Dr Mark Coles, University of York Project grant
Refinement of the use of fluid control as a motivational tool for non-human primates in neuroscience research Principal Investigator: Professor Alex Thiele, Newcastle University PhD Studentship
The development of an in vitro model of spinal cord injury to study aligned neurite outgrowth Principal Investigator: Professor Susan Barnett, University of Glasgow PhD Studentship
Characterisation and validation of an organotypic slice culture model of Alzheimer’s disease Principal Investigator: Dr Wendy Noble, King's College London PhD Studentship
Development of a non-animal model for characterizing drug-resistant tumours Principal Investigator: Professor Catherine Pears, University of Oxford PhD Studentship
A Drosophila model of Candida albicans gastrointestinal infection Principal Investigator: Professor Petros Ligoxygakis, University of Oxford PhD Studentship
Bone healing and regeneration in an ex vivo bioreactor – evaluation of angiogenesis and reparation for clinical application Principal Investigator: Professor Richard Oreffo, University of Southampton PhD Studentship
In vitro and in silico models of gut bacterial diversity and its impacts on human health Principal Investigator: Professor Timothy Barraclough, Imperial College London PhD Studentship
Development of non-radioactive labels for a receptor binding assay for paralytic shellfish poisoning (PSP) toxin testing Principal Investigator: Professor Christopher Elliott, Queen's University Belfast PhD Studentship
RETINAS: Origin retinas syringe insertion device Contractor: Allen Pearson, Origin Product Design Limited, CRACK IT Challenge
Optimisation of a flow-based human in vitro blood–brain barrier model to replace animal models for studying immunopathogenesis of viral brain infections Principal Investigator: Dr Adjanie Patabendige, University of Liverpool Fellowship
Reducing animal dependency in diabetes research through pancreatic stem cells Principal Investigator: Professor Mark Dunne, University of Manchester PhD Studentship
Construction of a miniaturised human lymph node model as an alternative to the Local Lymph Node Assay Principal Investigator: Professor Amir Ghaemmaghami, University of Nottingham PhD Studentship
Reduction & refinement in animal models of neuropathic pain: using systematic review & meta-analysis Principal Investigator: Dr Emily Sena, University of Edinburgh Project grant