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Refinement of soft tissue targeting and alignment protocols is small animal radiotherapy using an injectable fiducial marker

Institution: 

  • Queen's University Belfast
  • PhD Studentship

Moving the Adverse Outcome Pathways Framework towards Practical Utility by Integrating Compound Profiling Data and Using Deep Learning

Institution: 

  • University of Cambridge
  • PhD Studentship

Replacing animal models in fungal pathogen research: An in vitro Titan virulence assay for the human fungal pathogen Cryptococcus neoformans

Institution: 

  • University of Birmingham
  • PhD Studentship

3D hiPSC derived laminated retinal model as a tool for toxicology studies

  • CRACK IT Challenge

Microfluidic Automated Platform for Osteoarthritis Drug Screening (MA-PODS)

  • CRACK IT Challenge

Development of an AOP for cardiotoxicity mediated by the blockade of L-type calcium channel

Institution: 

  • Brunel University
  • Strategic grant

A chicken primary B cell culture model to study the pathogenesis and improve the control of immunosuppressive viruses of poultry

Institution: 

  • The Pirbright Institute
  • Project grant

Ex vivo model for the study of epicardium-targeted therapies

Institution: 

  • University of Surrey
  • Project grant

A technique to test novel methods of controlling poultry red mite in hens without performing field-scale trials

Institution: 

  • Moredun Research Institute
  • Project grant

A comprehensive in silico approach to measure spatio-temporal changes of bone tissue in mouse models of osteoporosis and osteoarthritis

Institution: 

  • University of Sheffield
  • Project grant

Development, validation and application of enhanced-welfare technology for wild small mammal research

Institution: 

  • University of Oxford
  • Project grant

Reducing the animal cost of CRISPR/Cas9 mutagenesis

Institution: 

  • University of Oxford
  • Project grant

Quantifying the potential of skin swabbing as a refinement for DNA sampling of laboratory fish

Institution: 

  • University of Leicester
  • Project grant

Replacing liver cancer models by modeling human liver cancer in vitro

Institution: 

  • University of Cambridge
  • Project grant

Human Tissue for Safety Pharmacology

  • Office-led project

Improving the predictive power of models for cancer research

  • Office-led project

Transfer of a non-human primate (NHP) in vitro functional assay for the early evaluation of TB vaccine candidates and the associated immune response

Institution: 

  • University of Oxford
  • Skills and Knowledge Transfer grant

High-throughput in vitro culture system for Cryptosporidium oocysts: replacing animals in research

Institution: 

  • Cardiff University
  • Skills and Knowledge Transfer grant

The use of PrP transgenic Drosophila to replace and reduce mice in the bioassay of mammalian prions

Institution: 

  • University of Cambridge
  • Skills and Knowledge Transfer grant

Dissemination of refinements in mouse experimental stroke models to the scientific community

Institution: 

  • University of Leicester
  • Skills and Knowledge Transfer grant

Design, Fabrication and Testing of a Mouse Embryo Culture Chip

  • CRACK IT Challenge

Chair restraint training of non-human primates

  • Office-led project

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